ReviewCurrent treatment options in cardiovascular medicine2016
Exercise and Aerobic Fitness to Reduce Cancer-Related Cardiovascular Toxicity.
Review in Current treatment options in cardiovascular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 15 citations in OpenAlex.
- Targeted therapies in non-small cell lung cancer and their cardiovascular impact: mechanisms, clinical profiles, and strategies of management.Frontiers in pharmacology · 2026Review
- Cardio-Oncology - A new subspecialty with collaboration at its heart.Indian heart journalReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementSeveral cancer treatments are associated with vascular toxicity, mainly mediated by their effects on endothelial cell function. In turn, vascular dysfunction may contribute to cardiac damage and other cardiovascular side effects such as hypertension, stroke, and arterial and venous thrombosis. Aerobic exercise is associated with numerous beneficial effects on the endothelium and on cardiovascular risk factors, and may potentially modulate some of the mechanisms of vascular damage associated with antineoplastic therapies, thereby reducing their cardiovascular toxicity. To date, only a very limited number of studies have focused on the effects of supervised exercise on endothelial function in cancer patients undergoing treatment and molecular mechanisms remain to be explored. Further mechanistic, translational, and clinical research is needed to investigate the potential protective role of exercise on the vascular toxicity of cancer treatments.
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