Evidence map›Paper›PMID 27180915›Full record

ReviewChest2016

Cystic Lung Diseases: Algorithmic Approach.

Suhail Raoof, Praveen Bondalapati, Ravikanth Vydyula, Jay H Ryu, Nishant Gupta, Sabiha Raoof, Jeff Galvin, Mark J Rosen, David Lynch, William Travis and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Chest, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 144 citations in OpenAlex.

  1. Evaluation of Cavitary Lung Lesions withMolecular imaging and radionuclide therapy · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Unusual presentation of a giant solitary lung cyst in an elderly gentleman.Indian journal of thoracic and cardiovascular surgery · 2024
    Article
  15. Article
  16. Review
  17. A 24-year-Old woman with recurrent pneumothoraces.Respiratory medicine case reports · 2024
    Article
  18. Review
  19. Lymphangioleiomyomatosis and Other Cystic Lung Diseases.Immunology and allergy clinics of North America · 2023
    Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 3 countries.

Suhail RaoofPulmonary Division, Lenox Hill Hospital. Electronic address: suhailraoof@gmail.com.
Praveen BondalapatiPulmonary Division, Lourdes Hospital.
Ravikanth VydyulaPulmonary Critical Care Division, Lenox Hill Hospital.
Jay H RyuPulmonary/CCM, Mayo Clinic.
Nishant GuptaPulmonary, Critical Care and Sleep Medicine, University of Cincinnati.
Sabiha RaoofDepartment of Radiology, Jamaica Hospital.
Jeff GalvinDepartment of Radiology, University of Maryland.
Mark J RosenPulmonary, Critical Care and Sleep Medicine, North Shore University Hospital.
David LynchDepartment of Radiology, National Jewish Health.
William TravisDepartment of Pathology, Memorial Sloan Kettering Cancer Center.
Sanjeev MehtaPulmonary Division, Lilavati Hospital.
Richard LazzaroDepartment of Thoracic Surgery, Lenox Hill Hospital, Northwell Health.
David NaidichDepartment of Radiology, NYU-Langone Medical Center.
Lenox Hill Hospital · USLilavati Hospital & Research Centre · INNorthwell Health · USMemorial Sloan Kettering Cancer Center · USNational Jewish Health · USNorth Shore University Hospital · USNYU Langone Health · USUniversity of Cincinnati · USUniversity of Technology, Jamaica · JM

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Cysts are commonly seen on CT scans of the lungs, and diagnosis can be challenging. Clinical and radiographic features combined with a multidisciplinary approach may help differentiate among various disease entities, allowing correct diagnosis. It is important to distinguish cysts from cavities because they each have distinct etiologies and associated clinical disorders. Conditions such as emphysema, and cystic bronchiectasis may also mimic cystic disease. A simplified classification of cysts is proposed. Cysts can occur in greater profusion in the subpleural areas, when they typically represent paraseptal emphysema, bullae, or honeycombing. Cysts that are present in the lung parenchyma but away from subpleural areas may be present without any other abnormalities on high-resolution CT scans. These are further categorized into solitary or multifocal/diffuse cysts. Solitary cysts may be incidentally discovered and may be an age related phenomenon or may be a remnant of prior trauma or infection. Multifocal/diffuse cysts can occur with lymphoid interstitial pneumonia, Birt-Hogg-Dubé syndrome, tracheobronchial papillomatosis, or primary and metastatic cancers. Multifocal/diffuse cysts may be associated with nodules (lymphoid interstitial pneumonia, light-chain deposition disease, amyloidosis, and Langerhans cell histiocytosis) or with ground-glass opacities (Pneumocystis jirovecii pneumonia and desquamative interstitial pneumonia). Using the results of the high-resolution CT scans as a starting point, and incorporating the patient's clinical history, physical examination, and laboratory findings, is likely to narrow the differential diagnosis of cystic lesions considerably.

Indexed as

AlgorithmsAmyloidosisBiopsyBirt-Hogg-Dube SyndromeBronchial NeoplasmsBronchiectasisCystsDiagnosis, DifferentialHistiocytosis, Langerhans-CellHumansLungLung DiseasesLung Diseases, InterstitialLung NeoplasmsPapillomaPneumonia, Pneumocystiscystic lung diseasediffuse lung diseasefocal lung luciencieslung cystspulmonary cysts

Identifiers

PMID27180915
PMCPMC7534033
OpenAlexW2352690127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.