ArticleJournal of diabetes investigation2016
Utility of hypertriglyceridemic waist phenotype for predicting incident type 2 diabetes: The Isfahan Diabetes Prevention Study.
Article in Journal of diabetes investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Lipid biomarkers for the prediction of type 2 diabetes risk, an umbrella review and updated meta-analyses of prospective observational studies.Frontiers in endocrinology · 2026Pooled it
- Hypertriglyceridemic waist phenotype and abnormal glucose metabolism: a system review and meta-analysis.Endocrine · 2019Pooled it
- Association between Hypertriglyceridemic-Waist Phenotype and Risk of Type 2 Diabetes Mellitus in Middle-Aged and Older Chinese Population: A Longitudinal Cohort Study.International journal of environmental research and public health · 2021Article
- Transition of Hypertriglyceridemic-Waist Phenotypes and the Risk of Type 2 Diabetes Mellitus among Middle-Aged and Older Chinese: A National Cohort Study.International journal of environmental research and public health · 2021Article
- Association of "hypertriglyceridemic waist" with increased 5-year risk of subclinical atherosclerosis in a multi-ethnic population: a prospective cohort study.BMC cardiovascular disorders · 2021Observational
- Comparison of the triglyceride-waist circumference and the C-reactive protein-waist circumference indices in nascent metabolic syndrome.International journal of physiology, pathophysiology and pharmacology · 2021Article
- Triglyceride is an independent predictor of type 2 diabetes among middle-aged and older adults: a prospective study with 8-year follow-ups in two cohorts.Journal of translational medicine · 2019Article
- Prevalence and relationship of hypertriglyceridaemic-waist phenotype and type 2 diabetes mellitus among a rural adult Chinese population.Public health nutrition · 2019Article
- The relationship between hypertriglyceridemic-waist phenotype and vitamin D status in type 2 diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Metabolic Syndrome, and Particularly the Hypertriglyceridemic-Waist Phenotype, Increases Breast Cancer Risk, and Adiponectin Is a Potential Mechanism: A Case-Control Study in Chinese Women.Frontiers in endocrinology · 2019Article
- Association between the Hypertriglyceridemic Waist Phenotype and Prediabetes in Chinese Adults Aged 40 Years and Older.Journal of diabetes research · 2018Article
- Response: Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension (Endocrinol Metab 2017;32:221-9, Mohsen Janghorbani et al.).Endocrinology and metabolism (Seoul, Korea) · 2017Article
- Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension.Endocrinology and metabolism (Seoul, Korea) · 2017Article
- Utility of hypertriglyceridemic waist phenotype for predicting incident type 2 diabetes: The Isfahan Diabetes Prevention Study.Journal of diabetes investigation · 2016Article
- Relationship Between Hypertriglyceridemic Waist Phenotype and Disposition Index in Chinese Men With Normal Glucose Tolerance.American journal of men's healthArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIM/
introductionWe evaluated the association between hypertriglyceridemic waist (HTW) phenotype and the risks of type 2 diabetes in an Iranian high-risk population. MATERIALS AND
methodsWe analyzed 7-year follow-up data (n = 1,865) in non-diabetic first-degree relatives of consecutive patients with type 2 diabetes aged 30-70 years. The primary outcome was the diagnosis of type 2 diabetes based on repeated oral glucose tolerance tests. We used multiple logistic regressions to estimate the odds ratio (OR) for incident type 2 diabetes across four groups according to baseline fasting serum triglycerides (TG) level and waist circumference (WC): normal WC and normal TG, normal WC and high TG, enlarged WC and normal TG, and HTW (enlarged WC high TG).
resultsThe HTW phenotype at baseline was associated with the incidence of type 2 diabetes. Those with HTW were 2.4-fold (OR 2.36, 95% confidence interval 1.61-3.44), those with normal WC high TG were 1.9-fold (OR 1.87, 95% confidence interval 1.29-2.70) and those with enlarged WC but normal TG were 2.8-fold (OR 2.84, 95% confidence interval 1.96-4.13) more likely to develop type 2 diabetes than those with normal WC and normal TG.
conclusionsThese data provide further evidence that the HTW phenotype is a robust predictor of type 2 diabetes in high-risk individuals in Iran, and the predictive power is not higher than that of simple enlarged WC and normal TG, emphasizing the importance of enlarged WC to the development of type 2 diabetes.
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