ReviewReviews in the neurosciences2016
Role of hippocampal activity-induced transcription in memory consolidation.
Review in Reviews in the neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Voluntary Physical Activity Modulates Brain ΔFOSB and Alters Coactivation Networks in Male and Female Mice.eNeuro · 2026Article
- Multi-omics characterization of chronic social defeat stress recall-activated nuclei in Arc-GFP mice.Molecular psychiatry · 2026Article
- Brain-wide induction of ΔFOSB and altered co-activation networks in a rat model for exercise training.Translational psychiatry · 2026Article
- Large-scale reorganization of DNA methylation and upregulation of extracellular matrix genes in the dorsal dentate gyrus following cocaine taking.bioRxiv : the preprint server for biology · 2026Article
- Protective Effects and Mechanism ofInternational journal of molecular sciences · 2024Article
- Aging differentially alters the transcriptome and landscape of chromatin accessibility in the male and female mouse hippocampus.Frontiers in molecular neuroscience · 2024Article
- Hippocampal and medial prefrontal ensemble spiking represents episodes and rules in similar task spaces.Cell reports · 2023Article
- Article
- Goal Choices Modify Frontotemporal Memory Representations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Prelimbic Ensembles Mediate Cocaine Seeking After Behavioral Acquisition and Once Rats Are Well-Trained.Frontiers in behavioral neuroscience · 2022Article
- DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons.iScience · 2021Article
- Serum- and glucocorticoid-inducible kinase 1 activity reduces dendritic spines in dorsal hippocampus.Neuroscience letters · 2020Article
- Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum.Molecular neurobiology · 2020Article
- Epigenetic Regulation of HippocampalThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Immediate and deferred epigenomic signatures of in vivo neuronal activation in mouse hippocampus.Nature neuroscience · 2019Article
- Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats.Neural plasticity · 2016Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Experience-dependent changes in the strength of connections between neurons in the hippocampus (HPC) are critical for normal learning and memory consolidation, and disruption of this process drives a variety of neurological and psychiatric diseases. Proper HPC function relies upon discrete changes in gene expression driven by transcription factors (TFs) induced by neuronal activity. Here, we describe the induction and function of many of the most well-studied HPC TFs, including cyclic-AMP response element binding protein, serum-response factor, AP-1, and others, and describe their role in the learning process. We also discuss the known target genes of many of these TFs and the purported mechanisms by which they regulate long-term changes in HPC synaptic strength. Moreover, we propose that future research in this field will depend upon unbiased identification of additional gene targets for these activity-dependent TFs and subsequent meta-analyses that identify common genes or pathways regulated by multiple TFs in the HPC during learning or disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.