Evidence map›Paper›PMID 27179621›Full record

ArticleTrends in immunology2016

Human Adaptive Natural Killer Cells: Beyond NKG2C.

Julia A Wagner, Todd A Fehniger

Open access · greenAbstract readComment
In one paragraph

Article in Trends in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. CD56Journal of leukocyte biology · 2020
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Julia A WagnerDepartment of Medicine, Division of Oncology, Washington University School of Medicine.
Todd A FehnigerDepartment of Medicine, Division of Oncology, Washington University School of Medicine. Electronic address: tfehnige@wustl.edu.
University of Washington · US

Funding

MICRORNA REGULATION OF NK CELL DEVELOPMENT AND FUNCTIONR01AI102924 · NIAID · WASHINGTON UNIVERSITY · PI FEHNIGER, TODD A · 2013 to 2016
$1.5M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI102924
6 · The paper itself

Abstract

Paradigm-shifting studies have identified NKG2C(+) adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C(-/-) HCMV(+) individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.

Indexed as

Adaptive ImmunityCD2 AntigensCytomegalovirusCytomegalovirus InfectionsHumansImmunity, InnateImmunologic MemoryInterleukin-12Interleukin-15Interleukin-18Killer Cells, NaturalLymphocyte ActivationNK Cell Lectin-Like Receptor Subfamily CReceptors, IgGCD2 AntigensFCGR3A protein, humanInterleukin-12Interleukin-15Interleukin-18KLRC2 protein, humanNK Cell Lectin-Like Receptor Subfamily CReceptors, IgG

Identifiers

PMID27179621
PMCPMC4885776
OpenAlexW2353571238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.