ArticleAllergy and asthma proceedings2016
Asthma and risk of breakthrough varicella infection in children.
Article in Allergy and asthma proceedings, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Artificial intelligence biomarker detects high-risk childhood asthma subgroup for respiratory infections and exacerbations.The Journal of allergy and clinical immunology · 2025Article
- Establishing an expert consensus for the operational definitions of asthma-associated infectious and inflammatory multimorbidities for computational algorithms through a modified Delphi technique.BMC medical informatics and decision making · 2021Article
- Risk, Mechanisms and Implications of Asthma-Associated Infectious and Inflammatory Multimorbidities (AIMs) among Individuals With Asthma: a Systematic Review and a Case Study.Allergy, asthma & immunology research · 2021Review
- A diagnostic codes-based algorithm improves accuracy for identification of childhood asthma in archival data sets.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021Article
- Clinical form of asthma and vaccine immunity in preschoolers.Postepy dermatologii i alergologii · 2021Article
- Clinical characteristics and risk factors associated with breakthrough varicella during varicella outbreaks.Human vaccines & immunotherapeutics · 2020Article
- A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children.Clinical and experimental vaccine research · 2019Article
- Early Identification of Childhood Asthma: The Role of Informatics in an Era of Electronic Health Records.Frontiers in pediatrics · 2019Review
- Asthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of Asthma.Tuberculosis and respiratory diseases · 2017Review
- New insights to the many aspects of asthma: "A disease of a thousand faces" Lon Chaney (1883-1930): The Man of a Thousand Faces.Allergy and asthma proceedings · 2016Article
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundWe recently reported a more rapid waning of vaccine-induced humoral immunity (measles vaccine) in children with asthma. It is unknown if asthma affects susceptibility to vaccine-preventable diseases.
objectiveTo determine whether asthma is associated with an increased risk of vaccine-preventable disease, e.g., breakthrough varicella infection.
methodsThis was a retrospective population-based case-control study that examined cases of breakthrough varicella among children between 2005 and 2011. Children with a diagnosis of breakthrough varicella infection in Olmsted County, Minnesota (infection of >42 days after vaccination) between 2005 and 2011 and two age- and sex-matched controls were enrolled for each case. Asthma status was determined by using predetermined criteria. Conditional logistic regression models were used to calculate matched odds ratios (OR) and their corresponding 95% confidence intervals (CI).
resultsOf the 165 cases and their 330 matched controls, 48% were boys and the mean (standard deviation) age at the index date was 6.6 ± 3.5 years for both cases and controls. Of the 330 controls, 80 (24%) had two doses of the varicella vaccine compared with only 23 (14%) of the 165 cases (OR 0.29 [95% CI, 0.14-0.61]; p = 0.001). Children with a history of asthma ever had a higher risk of developing breakthrough varicella compared with those without a history of asthma (adjusted OR 1.63 [95% CI, 1.04-2.55]; p = 0.032) when adjusting for elapsed time since the first varicella vaccination and the number of varicella vaccine doses.
conclusionsA history of asthma might be an unrecognized risk factor for breakthrough varicella infection. Children with asthma should follow the two-dose varicella vaccine policy.
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