Evidence map›Paper›PMID 27178608›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2016

Adolescent weight history and adult cognition: before and after bariatric surgery.

Mary Beth Spitznagel, Michael Alosco, Thomas H Inge, Amber Rochette, Gladys Strain, Michael Devlin, Ross D Crosby, James E Mitchell, John Gunstad

Abstract readMulticenter Study
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Response to Dr. Buchwald.Obesity surgery · 2024
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mary Beth SpitznagelKent State University, Kent, Ohio; Summa Health System, Akron, Ohio. Electronic address: mspitzna@kent.edu.
Michael AloscoKent State University, Kent, Ohio.
Thomas H IngeCincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio.
Amber RochetteKent State University, Kent, Ohio.
Gladys StrainWeill Cornell Medical College, New York, New York.
Michael DevlinColumbia University College of Physicians & Surgeons, New York, New York.
Ross D CrosbyNeuropsychiatric Research Institute and University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota.
James E MitchellNeuropsychiatric Research Institute and University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota.
John GunstadKent State University, Kent, Ohio; Summa Health System, Akron, Ohio.

Funding

ZIPRASIDONE IN NORMAL HEPATIC FUNCTION SUBJECTS &IN HEPATIC DYSFUCTIN SUBJECTSM01RR000037 · NCRR · UNIVERSITY OF WASHINGTON · PI PIHOKER, CATHERINE · 1985 to 2007
$33.8M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCCU01DK066557 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H. · 2003 to 2015
$15.8M
Adolescent Bariatrics: Assessing Health Benefits & RisksU01DK072493 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI INGE, THOMAS HARRIS · 2006 to 2010
$8.7M
BARIATRIC SURGERY CLINICAL RESEARCH CONSORTIUMU01DK066555 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI WOLFE, BRUCE M · 2003 to 2013
$6.2M
Effect of Bariatric Surgery on Insulin Resistance &CVDU01DK066585 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COURCOULAS, ANITA P · 2003 to 2013
$5.0M
Bariatric Surgery: Outcomes & Impact on PathophysiologyU01DK066667 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BERK, PAUL DAVID, POMP, ALFONS · 2003 to 2015
$4.7M
Longtitudinal Assessment of Bariatric Surgery (LABS)U01DK066568 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2003 to 2013
$4.3M
East Carolina University Bariatric Surgery Clinical CenterU01DK066526 · NIDDK · EAST CAROLINA UNIVERSITY · PI PORIES, WALTER JULIUS · 2003 to 2015
$4.0M
Longitudinal Assessment of Bariatric Surgery (LABS)U01DK066471 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2003 to 2015
$3.7M
Cognitive Effects of Bariatric SurgeryR01DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2006 to 2009
$1.5M
Extended Effects of Bariatric Surgery on Cognitive FunctionR56DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2010 to 2010
$296k
NCRR NIH HHS M01 RR000037NIDDK NIH HHS R01 DK075119NIDDK NIH HHS R56 DK075119NIDDK NIH HHS U01 DK066471NIDDK NIH HHS U01 DK066526NIDDK NIH HHS U01 DK066555NIDDK NIH HHS U01 DK066557NIDDK NIH HHS U01 DK066568NIDDK NIH HHS U01 DK066585NIDDK NIH HHS U01 DK066667NIDDK NIH HHS U01 DK072493
6 · The paper itself

Abstract

backgroundCognitive deficits occur in a subset of individuals with obesity. Deficits can be reversed with bariatric surgery, though cognitive recovery is not equally exhibited across patients. Recent work has found that obesity during adolescence portends medical complications in adulthood; it is unknown if obesity in adolescence predicts adult cognition or cognitive recovery after weight loss surgery.

objectivesThe present study examines the relationship between weight history and cognitive function in obese adults undergoing bariatric surgery.

settingAcademic medical centers with bariatric care services.

methodsSeventy-eight bariatric surgery patients (mean age = 43.2 years) enrolled in an ancillary study to the Longitudinal Assessment of Bariatric Surgery (LABS) project completed a questionnaire recalling weight history at age 18. Cognitive testing was completed preoperatively and at 12-month follow-up.

resultsWeight status at age 18 was linked to performance in several aspects of cognition. Higher body mass index at age 18 predicted poorer preoperative verbal fluency (B = -.26, P = .045) as well as postoperative cognitive recovery in attention (B = -.30, P = .01) at 12-month follow-up.

conclusionHigher body mass index at age 18 predicts verbal fluency performance in adults with obesity, as well as postoperative recovery of attention after bariatric surgery. The mechanisms underlying this connection are not fully clear, though findings may reflect effects of obesity on the brain during a crucial period of neural maturation or duration of obesity and cumulative impact of co-morbidities on cognition. Future work examining possible causal factors involved in these relationships is needed.

Indexed as

Bariatric SurgeryAdolescentAdultAnalysis of VarianceBody Mass IndexBody WeightCognition DisordersFemaleHumansMaleNeuropsychological TestsObesityPostoperative CarePostoperative ComplicationsPreoperative CareVerbal BehaviorBariatricCognitionObesityWeight history

Identifiers

PMID27178608
PMCPMC4967026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.