Evidence map›Paper›PMID 27178409›Full record

ReviewSeminars in immunopathology2016

New insights into basophil heterogeneity.

Landon K Oetjen, Mario Noti, Brian S Kim

Abstract readReview
In one paragraph

Review in Seminars in immunopathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Basophils in atopic dermatitis: Immunologic roles and clinical implications.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Review
  2. Review
  3. Article
  4. Temporal Modulation of Drug Desensitization Procedures.Current issues in molecular biology · 2022
    Review
  5. Skin-homing basophils and beyond.Frontiers in immunology · 2022
    Article
  6. Basophils in antihelminth immunity.Seminars in immunology · 2021
    Review
  7. Article
  8. Article
  9. Cytokine modulation of atopic itch.Current opinion in immunology · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Landon K OetjenDivision of Dermatology, Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8123, St. Louis, MO, 63110, USA.
Mario NotiDivision of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland.
Brian S KimDivision of Dermatology, Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8123, St. Louis, MO, 63110, USA. briankim@wustl.edu.

Funding

PRINCIPLES IN PULMONARY RESEARCHT32HL007317 · NHLBI · WASHINGTON UNIVERSITY · PI Steven Brody, Michael J Holtzman · 1985 to 2026
$16.1M
Innate Immune Regulation of Skin InflammationK08AR065577 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2014 to 2018
$711k
NHLBI NIH HHS T32 HL007317NIAMS NIH HHS K08 AR065577
6 · The paper itself

Abstract

Basophils have become increasingly recognized as important innate immune cells that mediate antihelminth immunity and barrier inflammation. Recent discoveries have uncovered previously unrecognized heterogeneity in basophil populations. However, how diversity in basophil regulation and function impacts human disease remains poorly defined. The goal of the present review is to highlight how new insights into basophil heterogeneity can help us to better understand disease pathogenesis and inform the development of new therapeutics.

Indexed as

AnimalsBasophilsBone Marrow CellsCell CommunicationCell DifferentiationCytokinesDisease SusceptibilityExtracellular SpaceHematopoiesisHematopoietic Stem CellsHumansImmunoglobulin EInterleukin-3Intracellular SpaceSignal TransductionThymic Stromal LymphopoietinCytokinesImmunoglobulin EInterleukin-3Thymic Stromal Lymphopoietin

Identifiers

PMID27178409
PMCPMC5010479

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.