ReviewTrends in immunology2016
Skin Immunity to Candida albicans.
Review in Trends in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A combination of photodynamic therapy and antimicrobial compounds to treat skin and mucosal infections: a systematic review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2019Pooled it
- Prevalence and Possible Role ofMediators of inflammation · 2018Pooled it
- Global translational reprogramming inVirulence · 2026Article
- A Keratinocyte-Mast Cell NF-κB2/CXCL2/IL-6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Infection by Different Clades of Candidozyma auris in a Galleria mellonella Model: Determining Virulence Levels.Mycopathologia · 2026Article
- Pseudolaric Acid B Combats Drug-Resistant Candida albicans Infection via Dual-Action Mechanisms of Direct Antifungals and Vaginal Microbiota Restoration.Microbial biotechnology · 2026Article
- Host-Candida auris interactions in the skin.PLoS pathogens · 2026Review
- Effect of Lactiplantibacillus Plantarum THK-J112 Against Candida Overgrowth in Acne Complications.Probiotics and antimicrobial proteins · 2026Article
- Iron acquisition mechanisms of human skin-associated fungi.FEMS yeast research · 2026Review
- Schiff base metal complexes as emerging therapeutics against antimicrobial-resistant skin pathogens.ADMET & DMPK · 2026Review
- Integrating Network Pharmacology and Experimental Validation: Mechanistic Study of the Anti-Plants (Basel, Switzerland) · 2025Article
- Article
- Cutaneous Innate Lymphoid Populations Drive IL-17A-Mediated Immunity in Nannizzia gypsea Dermatophytosis.The Journal of investigative dermatology · 2025Article
- Five-Year Retrospective Analysis of Superficial Fungal Infections: Insights from Hospital Experience.Journal of fungi (Basel, Switzerland) · 2025Article
- In Vitro and In Vivo Anti-Candida albicans Activity of a Scorpion-Derived Peptide.Probiotics and antimicrobial proteins · 2025Article
- Pinosylvin and Sanguinarine Combination to Enhance Antifungal Activity againstJournal of microbiology and biotechnology · 2025Article
- Synthesis and evaluation of the antifungal and antibiofilm potential of aminochalcones.Archives of microbiology · 2025Article
- Life stage impact on the human skin ecosystem: lipids and the microbial community.NPJ biofilms and microbiomes · 2025Article
- Thermoresponsive Gels with Rosemary Essential Oil: A Novel Topical Carrier for Antimicrobial Therapy and Drug Delivery Applications.Gels (Basel, Switzerland) · 2025Article
- The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach.BioImpacts : BI · 2025Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Candida albicans is a dimorphic commensal fungus that colonizes healthy human skin, mucosa, and the reproductive tract. C. albicans is also a predominantly opportunistic fungal pathogen, leading to disease manifestations such as disseminated candidiasis and chronic mucocutaneous candidiasis (CMC). The differing host susceptibilities for the sites of C. albicans infection have revealed tissue compartmentalization with tailoring of immune responses based on the site of infection. Furthermore, extensive studies of host genetics in rare cases of CMC have identified conserved genetic pathways involved in immune recognition and the response to the extracellular pathogen. We focus here on human and mouse skin as a site of C. albicans infection, and we review established and newly discovered insights into the cellular pathways that promote cutaneous antifungal immunity.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.