ArticleSurgical endoscopy2016
Surgical management of empyematous cholecystitis: a register study of over 12,000 cases from a regional quality control database in Germany.
Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Preoperative prediction of acute severe cholecystitis using an attentive interpretable tabular network (TabNet)-based radiomics model and a stacking ensemble: a two-center study.Annals of medicine · 2026Article
- Deep learning enables accurate diagnosis of acute cholecystitis and prediction of suppuration using noncontrast CT.iScience · 2025Article
- LIPUS Enhances Gallbladder Motility via ANO1 in Acute Cholecystitis Guinea Pigs.Bioengineering (Basel, Switzerland) · 2025Article
- From the operating room: Surgeons' views on difficult laparoscopic cholecystectomies.Annals of hepato-biliary-pancreatic surgery · 2025Article
- Optimal timing for cholecystectomy: unveiling insights from a decade-long study on acute cholecystitis and symptomatic cholecystolithiasis.BMC surgery · 2025Article
- Timing of Elective Cholecystectomy After Acute Cholecystitis: A Population-based Register Study.World journal of surgery · 2023Article
- Value of nonenhanced CT combined with laboratory examinations in the diagnosis of acute suppurative cholecystitis treated with percutaneous cholecystostomy: a retrospective study.BMC gastroenterology · 2022Article
- Novel Use of Intraoperative Fluoroscopy in an Era of ICG for Complex Laparoscopic Cholecystectomy.Surgery journal (New York, N.Y.) · 2021Article
- Uncommon Presentation of Severe Empyema of the Gallbladder: Case Report and Literature Review.The American journal of case reports · 2020Review
- The impossible gallbladder: aspiration as an alternative to conversion.Surgical endoscopy · 2020Article
- The role of indocyanine green fluoroscopy for intraoperative bile duct visualization during laparoscopic cholecystectomy: an observational cohort study in 70 patients.Patient safety in surgery · 2019Article
- Advanced gallbladder inflammation is a risk factor for gallbladder perforation in patients with acute cholecystitis.World journal of emergency surgery : WJES · 2018Article
- Acute cholecystitis - a cohort study in a real-world clinical setting (REWO study, NCT02796443).Pragmatic and observational research · 2018Article
- Metastatic Gallbladder Melanoma Presenting as Acute Emphysematous Cholecystitis.Case reports in medicine · 2018Article
- Outcome of acute perforated cholecystitis: a register study of over 5000 cases from a quality control database in Germany.Surgical endoscopy · 2017Article
- Acute cholecystitis complicated with gallbladder empyema due toTherapeutic advances in infectious diseaseArticle
- Indocyanine green: An old drug with novel applications.Tzu chi medical journalReview
- Gall Bladder Empyema: Early Cholecystectomy during the Index Admission Improves Outcomes.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute cholecystitis is a common indication for surgery. Surgical outcomes depend among other factors on the extent of gallbladder inflammation. Data on the outcomes of patients undergoing cholecystectomy due to acute empyematous cholecystitis are rare.
methodsData from a prospectively maintained quality control database in Germany were analyzed. Cases with empyematous cholecystitis were compared to cases without gallbladder empyema with regard to baseline features, clinical parameters and surgical outcomes.
resultsA total of 12,069 patients with empyematous cholecystitis (EC) were compared to 33,296 patients without empyema. The male gender, advanced age, ASA score >2, elevated white blood count and fever were confirmed as risk factors for EC. The EC group differed significantly from the control group with regard to fever (28.0 vs. 9.5 %), elevated WBC (82.5 vs. 62.3 %) and positive findings from ultrasound sonography (87.4 vs. 76.9 %), p < 0001. Surgery lasted significantly longer in the EC group (86.1 ± 38.5 vs. 72.2 ± 33.6, p < 0.001). The rates of conversion (15.2 vs. 5.8 %), bile duct injury (0.8 vs. 0.4 %), re-intervention (5.5 vs. 2.6 %) and mortality (2.8 vs. 1.2 %) were significantly higher in the EC group, p < 0.001. Similarly, the length of stay (11.9 ± 10.5 vs. 8.8 ± 8.3, p < 0.001) was significantly longer in the EC group.
conclusionEmpyematous cholecystitis is a severe form of acute cholecystitis with high rates of morbidity and mortality. Even the experienced laparoscopic surgeon should expect dissection difficulties, therefore the threshold for conversion in order to prevent bile duct injury should be low.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.