ReviewCurrent rheumatology reports2016
Non-invasive Loading Model of Murine Osteoarthritis.
Review in Current rheumatology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Experimental models of osteoarthritis: Advances, limitations and rational selection for translational research.Journal of orthopaedic translation · 2026Review
- Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration.Science (New York, N.Y.) · 2026Article
- Knee osteoarthritis: A review of animal models and intervention of traditional Chinese medicine.Animal models and experimental medicine · 2024Review
- Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated pain.Arthritis research & therapy · 2024Article
- A synoptic literature review of animal models for investigating the biomechanics of knee osteoarthritis.Frontiers in bioengineering and biotechnology · 2024Review
- Review
- Collagenase-Induced Osteoarthritis in Mice.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Collagenase-Induced Mouse Model of Osteoarthritis-A Thorough Flow Cytometry Analysis.Life (Basel, Switzerland) · 2022Article
- Characterization of Non-Invasively Induced Post-Traumatic Osteoarthritis in Mice.Antioxidants (Basel, Switzerland) · 2022Article
- Induction of Accelerated Aging in a Mouse Model.Cells · 2022Review
- Mouse Models of Osteoarthritis: A Summary of Models and Outcomes Assessment.Comparative medicine · 2022Review
- Infrapatellar Fat Pad-Synovial Membrane Anatomo-Fuctional Unit: Microscopic Basis for Piezo1/2 Mechanosensors Involvement in Osteoarthritis Pain.Frontiers in cell and developmental biology · 2022Article
- Understanding Early-Stage Posttraumatic Osteoarthritis for Future Prospects of Diagnosis: from Knee to Temporomandibular Joint.Current osteoporosis reports · 2021Review
- Current Models for Development of Disease-Modifying Osteoarthritis Drugs.Tissue engineering. Part C, Methods · 2021Review
- Osteoarthritis Affects Mammalian Oogenesis: Effects of Collagenase-Induced Osteoarthritis on Oocyte Cytoskeleton in a Mouse Model.International journal of inflammation · 2021Article
- Effect of whole body vibration on HIF-2α expression in SD rats with early knee osteoarthritis.Journal of bone and mineral metabolism · 2020Article
- Mechanobiological Mechanisms of Load-Induced Osteoarthritis in the Mouse Knee.Journal of biomechanical engineering · 2019Article
- Pros and cons of mouse models for studying osteoarthritis.Clinical and translational medicine · 2018Review
- Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models.Arthritis research & therapy · 2017Article
- The STR/ort mouse model of spontaneous osteoarthritis - an update.Osteoarthritis and cartilage · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Osteoarthritis is the commonest degenerative joint disease, leading to joint pain and disability. The mouse has been the primary animal used for research, due to its size, relatively short lifespan, and the availability of genetically modified animals. Importantly, they show pathogenesis similar to osteoarthritis in humans. Mechanical loading is a major risk factor for osteoarthritis, and various mouse models have been developed to study the role and effects of mechanics on health and disease in various joints. This review describes the main mouse models used to non-invasively apply mechanical loads on joints. Most of the mouse models of osteoarthritis target the knee, including repetitive loading and joint injury such as ligament rupture, but a few studies have also characterised models for elbow, temporomandibular joint, and whole-body vibration spinal loading. These models are a great opportunity to dissect the influences of various types of mechanical input on joint health and disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.