ArticleEnvironmental science & technology2016
Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials.
Article in Environmental science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed.
- Probabilistically defining environmentally relevant concentrations in ecotoxicology.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Analysis and Risks of Emerging Contaminants and Microplastics in Natural and Treated Waters and Human Health: A Critical Review.Journal of xenobiotics · 2026Review
- The nano-paradox: addressing nanotoxicity for sustainable agriculture, circular economy and SDGs.Journal of nanobiotechnology · 2025Review
- Article
- Plant mediated fabrication of silver nanoparticles, process optimization, and impact on tomato plant.Scientific reports · 2023Article
- Particle-Driven Effects at the Bacteria Interface: A Nanosilver Investigation of Particle Shape and Dose Metric.ACS applied materials & interfaces · 2023Article
- Green Synthesized Silver Nanoparticles: A Novel Approach for the Enhanced Growth and Yield of Tomato against Early Blight Disease.Microorganisms · 2023Article
- Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives.Journal of nanobiotechnology · 2023Review
- Nanomaterials Induced Genotoxicity in Plant: Methods and Strategies.Nanomaterials (Basel, Switzerland) · 2022Review
- Aquatic organisms modulate the bioreactivity of engineered nanoparticles: focus on biomolecular corona.Frontiers in toxicology · 2022Review
- Biosynthesized silver nanoparticles induce phytotoxicity inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Low Toxicological Impact of Commercial Pristine Multi-Walled Carbon Nanotubes on the YeastNanomaterials (Basel, Switzerland) · 2021Article
- Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science and a Proposed Path Forward.Environmental toxicology and chemistry · 2021Review
- Influence of Cerium Oxide Nanoparticles on Two Terrestrial Wild Plant Species.Plants (Basel, Switzerland) · 2021Article
- Single and Repeated Applications of Cerium Oxide Nanoparticles Differently Affect the Growth and Biomass Accumulation ofNanomaterials (Basel, Switzerland) · 2021Article
- Assessment of Physico-Chemical and Toxicological Properties of Commercial 2D Boron Nitride Nanopowder and Nanoplatelets.International journal of molecular sciences · 2021Article
- Molecular Mechanisms of Nanomaterial-Bacterial Interactions Revealed by Omics-The Role of Nanomaterial Effect Level.Frontiers in bioengineering and biotechnology · 2021Review
- Ecological Drawbacks of Nanomaterials Produced on an Industrial Scale: Collateral Effect on Human and Environmental Health.Water, air, and soil pollution · 2021Review
- Germination and Early Development of Three Spontaneous Plant Species Exposed to Nanoceria (Nanomaterials (Basel, Switzerland) · 2020Article
- Recent Developments in the Application of Nanomaterials in Agroecosystems.Nanomaterials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
40 authors.
Funding
Abstract
Engineered nanomaterials (ENMs) are increasingly entering the environment with uncertain consequences including potential ecological effects. Various research communities view differently whether ecotoxicological testing of ENMs should be conducted using environmentally relevant concentrations-where observing outcomes is difficult-versus higher ENM doses, where responses are observable. What exposure conditions are typically used in assessing ENM hazards to populations? What conditions are used to test ecosystem-scale hazards? What is known regarding actual ENMs in the environment, via measurements or modeling simulations? How should exposure conditions, ENM transformation, dose, and body burden be used in interpreting biological and computational findings for assessing risks? These questions were addressed in the context of this critical review. As a result, three main recommendations emerged. First, researchers should improve ecotoxicology of ENMs by choosing test end points, duration, and study conditions-including ENM test concentrations-that align with realistic exposure scenarios. Second, testing should proceed via tiers with iterative feedback that informs experiments at other levels of biological organization. Finally, environmental realism in ENM hazard assessments should involve greater coordination among ENM quantitative analysts, exposure modelers, and ecotoxicologists, across government, industry, and academia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.