ArticleMedicine2016
Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired Acute Kidney Injury: A Retrospective Cohort Study.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06051708 (Risk Factors And Outcomes Of Hospital Acquired Acute Kidney Injury), which is not on this map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors And Outcomes Of Hospital Acquired Acute Kidney Injury: A Tertiary Health Care Center Experience
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Incidence and risk factors of acute kidney injury in patients with polypharmacy: a systematic review and meta-analysis.International journal of clinical pharmacy · 2025Pooled it
- Early initiation of renal replacement treatment in patients with acute kidney injury: A systematic review and meta-analysis.Medicine · 2016Pooled it
- Mechanisms of regeneration and maladaptive repair in acute kidney injury.Nature reviews. Nephrology · 2026Review
- The impact of social determinants of health on acute kidney injury.Nature reviews. Nephrology · 2026Review
- Outcomes of community-acquired acute kidney injury: a prospective comparative cohort study.BMC nephrology · 2025Article
- Risk factors and prognosis of post-surgical acute kidney injury in elderly patients based on the MIMIC-IV database.European journal of medical research · 2025Review
- Estimating the Association Between Outdoor Temperature and Acute Kidney Injury Using Alternative Case Definitions.Journal of occupational and environmental medicine · 2025Article
- Acute kidney injury does not explain sex differences in kidney replacement therapy initiation or death amongst individuals with chronic kidney disease reported to the UK Renal Registry.Clinical kidney journal · 2025Article
- Outcomes of Community-Acquired Acute Kidney Injury: A Cohort Study of US Veterans.Medical care · 2025Article
- Evaluating the kidney disease progression using a comprehensive patient profiling algorithm: A hybrid clustering approach.PloS one · 2025Article
- Sociodemographic Disparities in 1-Year Outcomes of Children With Community-Acquired Acute Kidney Injury.JAMA network open · 2024Article
- Prevalent and new use of common drugs for the incidence of community-acquired acute kidney injury: cohort and case-crossover study.Scientific reports · 2024Article
- Differences in the epidemiology, management and outcomes of kidney disease in men and women.Nature reviews. Nephrology · 2024Review
- Characteristics, Risk Factors, and Outcomes in Acute Kidney Injury Patients: A Retrospective Cross-Sectional Study, Palestine.TheScientificWorldJournal · 2024Article
- Clinical characteristics and outcomes of community acquired-acute kidney injury.International urology and nephrology · 2023Article
- Epidemiology of Community-Acquired Acute Kidney Injury Among US Veterans.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Prognosis and mortality within 90 days in community-acquired acute kidney injury in the Southwest of Sweden.BMC nephrology · 2023Article
- Hospitalisation Due to Community-Acquired Acute Kidney Injury and the Role of Medications: A Retrospective Audit.Journal of clinical medicine · 2023Article
- Elevation of serum human epididymis protein 4 (HE4) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) as predicting factors for the occurrence of acute kidney injury on chronic kidney disease: a single-center retrospective self-control study.Frontiers in pharmacology · 2023Article
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Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The disease burden and outcomes of community-acquired (CA-) and hospital-acquired acute kidney injury (HA-AKI) are not well understood. The aim of the study was to investigate the incidence, outcomes, and risk factors of AKI in a large Taiwanese adult cohort.This retrospective cohort study examined 734,340 hospital admissions from a group of hospitals within an organization in Taiwan between January 1, 2010 and December 31, 2014. Patients with AKI at discharge were classified as either CA- or HA-AKI based on the RIFLE (risk, injury, failure, loss of function, end stage of kidney disease) classification criteria. Outcomes were in-hospital mortality, dialysis, recovery of renal function, and length of stay. Risks of developing AKI were determined using multivariate logistic regression based on demographic and baseline clinical characteristics and nephrotoxin use before admission.AKI occurred in 1.68% to 2% hospital discharges among adults without and with preexisting chronic kidney disease (CKD), respectively. The incidence of CA-AKI was 17.25 and HA-AKI was 8.14 per 1000 admissions. The annual rate of CA-AKI increased from 12.43 to 19.96 per 1000 people, but the change in HA-AKI was insignificant. Comparing to CA-AKI, those with HA-AKI had higher levels of in-hospital mortality (26.07% vs 51.58%), mean length of stay (21.25 ± 22.35 vs 35.84 ± 34.62 days), and dialysis during hospitalization (1.45% vs 2.06%). Preexisting systemic diseases, including CKD were associated with increased risks of CA-AKI, and nephrotoxic polypharmacy increased risk of both CA- and HA-AKI.Patients with HA-AKI had more severe outcomes than patients with CA-AKI, and demonstrated different spectrum of risk factors. Although patients with CA-AKI with better outcomes, the incidence increased over time. It is also clear that optimal preventive and management strategies of HA- and CA-AKI are urgently needed to limit the risks in susceptible individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.