Evidence map›Paper›PMID 27175670›Full record

ArticleMedicine2016

Evaluation of Two New Indices of Blood Pressure Variability Using Postural Change in Older Fallers.

Choon-Hian Goh, Siew-Cheok Ng, Shahrul B Kamaruzzaman, Ai-Vyrn Chin, Philip J H Poi, Kok Han Chee, Z Abidin Imran, Maw Pin Tan

Abstract readEvaluation Study
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Choon-Hian GohFrom the Ageing and Age-Associated Disorders Research Group, Faculty of Medicine, University of Malaya (C-HG, SBK, A-VC, PJHP, MPT), Department of Biomedical Engineering, Faculty of Engineering, University of Malaya (C-HG, S-CN), Division of Geriatric Medicine, Department of Medicine, Faculty of Medicine, University of Malaya (SBK, A-VC, PJHP, MPT), and Division of Cardiology, Department of Medicine (KHC, ZAI), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Siew-Cheok Ng
Shahrul B Kamaruzzaman
Ai-Vyrn Chin
Philip J H Poi
Kok Han Chee
Z Abidin Imran
Maw Pin Tan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the utility of blood pressure variability (BPV) calculated using previously published and newly introduced indices using the variables falls and age as comparators.While postural hypotension has long been considered a risk factor for falls, there is currently no documented evidence on the relationship between BPV and falls.A case-controlled study involving 25 fallers and 25 nonfallers was conducted. Systolic (SBPV) and diastolic blood pressure variability (DBPV) were assessed using 5 indices: standard deviation (SD), standard deviation of most stable continuous 120 beats (staSD), average real variability (ARV), root mean square of real variability (RMSRV), and standard deviation of real variability (SDRV). Continuous beat-to-beat blood pressure was recorded during 10 minutes' supine rest and 3 minutes' standing.Standing SBPV was significantly higher than supine SBPV using 4 indices in both groups. The standing-to-supine-BPV ratio (SSR) was then computed for each subject (staSD, ARV, RMSRV, and SDRV). Standing-to-supine ratio for SBPV was significantly higher among fallers compared to nonfallers using RMSRV and SDRV (P = 0.034 and P = 0.025). Using linear discriminant analysis (LDA), 3 indices (ARV, RMSRV, and SDRV) of SSR SBPV provided accuracies of 61.6%, 61.2%, and 60.0% for the prediction of falls which is comparable with timed-up and go (TUG), 64.4%.This study suggests that SSR SBPV using RMSRV and SDRV is a potential predictor for falls among older patients, and deserves further evaluation in larger prospective studies.

Indexed as

Accidental FallsHealth Status IndicatorsAgedAged, 80 and overBlood PressureBlood Pressure DeterminationCase-Control StudiesDiscriminant AnalysisFemaleHumansHypotension, OrthostaticMalePosturePredictive Value of TestsRisk Assessment

Identifiers

PMID27175670
PMCPMC4902512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.