ArticlePloS one2016
Characterization and Genetic Analysis of a Novel Light-Dependent Lesion Mimic Mutant, lm3, Showing Adult-Plant Resistance to Powdery Mildew in Common Wheat.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 50 citations in OpenAlex.
- Characterization, genetic analysis and gene identification of an EMS-mutagenized lesion-mimic mutant with enhanced powdery mildew resistance in bread wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- A Transmembrane Protein WAI-B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Genome-wide dissection of lesion mimic mutations in wheat: identification and functional characterization of candidate genes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Mapping, cloning, and functional characterization of CsPBGD in leaf necrosis and its potential role in disease resistance in cucumber (Cucumis sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Lesion Mimic Mutant: An Ideal Genetic Material for Deciphering the Balance Between Plant Immunity and Growth.Rice (New York, N.Y.) · 2025Review
- Characterization and Fine Mapping of the Stay-Green-Related Spot Leaf GeneInternational journal of molecular sciences · 2025Article
- Article
- Disruption of the Novel Small Protein RBR7 Leads to Enhanced Plant Resistance to Blast Disease.Rice (New York, N.Y.) · 2023Article
- A dominant gene Ihrl1 is tightly linked to and inhibits the gene Ndhrl1 mediating nitrogen-dependent hypersensitive reaction-like phenotype in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- ATP-citrate lyase B (ACLB) negatively affects cell death and resistance to Verticillium wilt.BMC plant biology · 2022Article
- Cloning the barley nec3 disease lesion mimic mutant using complementation by sequencing.The plant genome · 2022Article
- Characterization and fine mapping of a lesion mimic mutant (Lm5) with enhanced stripe rust and powdery mildew resistance in bread wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Role of reactive oxygen species in lesion mimic formation and conferred basal resistance toFrontiers in plant science · 2022Article
- Enhanced SA and CaMolecular genetics and genomics : MGG · 2021Article
- Cotton GhSSI2 isoforms from the stearoyl acyl carrier protein fatty acid desaturase family regulate Verticillium wilt resistance.Molecular plant pathology · 2021Article
- Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat.BMC genomic data · 2021Article
- Plant Defense Responses to Biotic Stress and Its Interplay With Fluctuating Dark/Light Conditions.Frontiers in plant science · 2021Review
- Commonly and Specifically Activated Defense Responses in Maize Disease Lesion Mimic Mutants Revealed by Integrated Transcriptomics and Metabolomics Analysis.Frontiers in plant science · 2021Article
- Genetic characterization for lesion mimic and other traits in relation to spot blotch resistance in spring wheat.PloS one · 2020Article
- Identification and characterization of a spotted-leaf mutant spl40 with enhanced bacterial blight resistance in rice.Rice (New York, N.Y.) · 2019Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lesion mimics (LMs) that exhibit spontaneous disease-like lesions in the absence of pathogen attack might confer enhanced plant disease resistance to a wide range of pathogens. The LM mutant, lm3 was derived from a single naturally mutated individual in the F1 population of a 3-1/Jing411 cross, backcrossed six times with 3-1 as the recurrent parent and subsequently self-pollinated twice. The leaves of young seedlings of the lm3 mutant exhibited small, discrete white lesions under natural field conditions. The lesions first appeared at the leaf tips and subsequently expanded throughout the entire leaf blade to the leaf sheath. The lesions were initiated through light intensity and day length. Histochemical staining revealed that lesion formation might reflect programmed cell death (PCD) and abnormal accumulation of reactive oxygen species (ROS). The chlorophyll content in the mutant was significantly lower than that in wildtype, and the ratio of chlorophyll a/b was increased significantly in the mutant compared with wildtype, indicating that lm3 showed impairment of the biosynthesis or degradation of chlorophyll, and that Chlorophyll b was prone to damage during lesion formation. The lm3 mutant exhibited enhanced resistance to wheat powdery mildew fungus (Blumeria graminis f. sp. tritici; Bgt) infection, which was consistent with the increased expression of seven pathogenesis-related (PR) and two wheat chemically induced (WCI) genes involved in the defense-related reaction. Genetic analysis showed that the mutation was controlled through a single partially dominant gene, which was closely linked to Xbarc203 on chromosome 3BL; this gene was delimited to a 40 Mb region between SSR3B450.37 and SSR3B492.6 using a large derived segregating population and the available Chinese Spring chromosome 3B genome sequence. Taken together, our results provide information regarding the identification of a novel wheat LM gene, which will facilitate the additional fine-mapping and cloning of the gene to understand the mechanism underlying LM initiation and disease resistance in common wheat.
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