Evidence map›Paper›PMID 27175282›Full record

ArticleBMC sports science, medicine & rehabilitation2016

The feasibility of progressive resistance training in women with polycystic ovary syndrome: a pilot randomized controlled trial.

Lisa Vizza, Caroline A Smith, Soji Swaraj, Kingsley Agho, Birinder S Cheema

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03362918 (The Impact of Continuous Aerobic Exercise and High-Intensity Interval Training on Reproductive Outcomes in Polycystic Ovary Syndrome), which is not on this map. Cited by 39 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 19 pooled it
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03362918 nacompletednot on this mapstarted 2018, after this paper: background citation

The Impact of Continuous Aerobic Exercise and High-Intensity Interval Training on Reproductive Outcomes in Polycystic Ovary Syndrome: A Pilot Randomized Controlled Trial.

TypeinterventionalSponsorUniversity of CalgaryRan2018 to 2020Enrolled60ConditionsPolycystic Ovary SyndromeArmsHigh Intensity Interval Training, Continuous Aerobic Exercise Training
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 19 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  7. Effects of physical activity in women with polycystic ovary syndrome: a systematic review and meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
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  15. Lifestyle changes in women with polycystic ovary syndrome.The Cochrane database of systematic reviews · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lisa VizzaSchool of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751 Australia.
Caroline A SmithThe National Institute of Complementary Medicine, Western Sydney University, Penrith, NSW 2751 Australia.
Soji SwarajDepartment of Endocrinology, Concord Repatriation General Hospital, Concord West, NSW 2138 Australia.
Kingsley AghoSchool of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751 Australia.
Birinder S CheemaSchool of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751 Australia ; The National Institute of Complementary Medicine, Western Sydney University, Penrith, NSW 2751 Australia.
Western Sydney University · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the feasibility of executing a randomized controlled trial of progressive resistance training (PRT) in women with polycystic ovary syndrome (PCOS).

methodsWomen with PCOS were randomized to an experimental (PRT) group or a no-exercise (usual care) control group. The PRT group was prescribed two supervised and two unsupervised (home-based) training sessions per week for 12 weeks. Feasibility outcomes included recruitment and attrition, adherence, adverse events, and completion of assessments. Secondary outcomes, collected pre and post intervention, included a range of pertinent physiological, functional and psychological measures.

resultsFifteen participants were randomised into the PRT group (n = 8) or control group (n = 7); five women (n = 2 in PRT group and n = 3 in control group) withdrew from the study. The most successful recruitment sources were Facebook (40 %) and online advertisement (27 %), while least successful methods were referrals by clinicians, colleagues and flyers. In the PRT group, attendance to supervised sessions was higher (95 %; standard deviation ±6 %) compared to unsupervised sessions (51 %; standard deviation ±28 %). No adverse events were attributed to PRT. Change in menstrual cycle status was not significantly different between groups over time (p = 0.503). However, the PRT group significantly increased body weight (p = 0.01), BMI (p = 0.04), lean mass (p = 0.01), fat-free mass (p = 0.005) and lower body strength (p = 0.03), while reducing waist circumference (p = 0.03) and HbA1c (p = 0.033) versus the control group. The PRT group also significantly improved across several domains of disease-specific and general health-related quality of life, depression, anxiety and exercise self-efficacy.

conclusionA randomized controlled trial of PRT in PCOS would be feasible, and this mode of exercise may elicit a therapeutic effect on clinically important outcomes in this cohort. The success of a large-scale trial required to confirm these findings would be contingent on addressing the feasibility hurdles identified in this study with respect to recruitment, attrition, compliance, and collection of standardized clinical data.

trial registrationAustralia New Zealand Clinical Trials Registry; ACTRN12614000517673 Registered 15 May 2014.

Indexed as

ExerciseMenstrual cyclicityPsychological healthQuality of lifeWeight training

Identifiers

PMID27175282
PMCPMC4865007
OpenAlexW2366353819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.