ArticleNeuropsychiatric disease and treatment2016
Risk factors for pneumonia among patients with Parkinson's disease: a Taiwan nationwide population-based study.
Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Case Definitions and Data Sources for NNCSS Parkinson Disease Surveillance: A Systematic Review.JAMA network open · 2026Pooled it
- Periodontitis and Parkinson's disease: a narrative review of associations, proposed mechanisms, and clinical considerations.Frontiers in oral health · 2026Review
- Correlation between aging, periodontal diagnoses and systemic diseases: a retrospective analysis of 3,000 patients.BMC oral health · 2025Article
- Far from being the end of the road: taking a closer look at neuropalliative care in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Article
- Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients.Annals of rehabilitation medicine · 2023Article
- SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19.Journal of neuropathology and experimental neurology · 2022Article
- Bacterial etiology and mortality rate in community-acquired pneumonia, healthcare-associated pneumonia and hospital-acquired pneumonia in Thai university hospital.Scientific reports · 2022Article
- Relationship Between Pneumonia and Dysphagia in Patients With Multiple System Atrophy.Frontiers in neurology · 2022Article
- Acute Brain Ischemia, Infarction and Hemorrhage in Subjects Dying with or Without Autopsy-Proven Acute Pneumonia.medRxiv : the preprint server for health sciences · 2021Article
- The Prevalence of Anticholinergic Drugs and Correlation with Pneumonia in Elderly Patients: A Population-Based Study in Taiwan.International journal of environmental research and public health · 2020Article
- Neurological manifestations and implications of COVID-19 pandemic.Therapeutic advances in neurological disorders · 2020Review
- Risk factors for depression in patients with Parkinson's disease: A nationwide nested case-control study.PloS one · 2020Article
- Dental Scaling Decreases the Risk of Parkinson's Disease: A Nationwide Population-Based Nested Case-Control Study.International journal of environmental research and public health · 2018Article
- Manifestations and Outcomes of Patients with Parkinson's Disease and Serious Infection in the Emergency Department.BioMed research international · 2018Observational
- Article
- Botulinum toxin A for sialorrhea in adults with neurological disorders: a narrative review of aspiration pneumonia risk.Frontiers in neurologyReview
- Oral Health Disorders in Parkinson's Disease: More than Meets the Eye.Journal of Parkinson's diseaseReview
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePneumonia is the leading cause of death in patients with Parkinson's disease (PD). However, few studies have been performed to explore the risk factors for pneumonia development in patients with PD.
methodsWe conducted a nationwide population-based cohort study of patients with PD to identify the risk factors for these patients developing pneumonia. Participants with newly diagnosed PD between 2000 and 2009 were enrolled from the 2000-2010 National Health Insurance Research Database in Taiwan. We compared patients with PD with an incidence of hospitalization with pneumonia vs those without, and Cox proportional hazard models were used to estimate the risk of pneumonia.
resultsOf the 2,001 enrolled patients (mean follow-up duration 5.8 years, range: 2.7-14.7 years), 381 (19.0%) had an incidence of hospitalization with pneumonia during the study period. Multivariate Cox proportional hazards analysis identified older age group (≥80 years of age, hazard ratio [HR] =3.15 [95% confidence interval 2.32-4.28]), male sex (HR =1.59 [1.29-1.96]), certain geographic regions (northern, HR =1.36 [1.04-1.78], southern and eastern, HR =1.40 [1.05-1.88]), rural areas (HR =1.34 [1.05-1.72]), chronic heart failure (HR =1.53 [1.02-2.29]), and chronic kidney disease (HR =1.39 [1.03-1.90]) as risk factors for hospitalization with pneumonia in patients with PD. However, treatment for dental caries was a protective factor (HR =0.80 [0.64-0.99]).
conclusionThe results of this study highlight risk factors that are associated with hospitalization with pneumonia, and, for the first time, suggest a link between treated dental caries and a diminished risk of hospitalization with pneumonia in patients with PD.
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