Evidence map›Paper›PMID 27174580›Full record

Trial reportPediatric diabetes2017

Premeal insulin decreases arterial stiffness in children with type 1 diabetes.

Colette S Meehan, Pooja L Kethireddy, Jordan K Ashcraft, Jonathan J Shuster, Michael J Haller

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatric diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Vascular ageing: moving from bench towards bedside.European journal of preventive cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Colette S MeehanDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Pooja L KethireddyDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Jordan K AshcraftDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Jonathan J ShusterDepartment of Health Outcomes and Policy Biostatistics Epidemiology and Research Design, Clinical Translational Science Institute, University of Florida, Gainesville, FL 32610, USA.
Michael J HallerDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
University of Florida · USUniversity of Florida Health · US

Funding

UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
NCATS NIH HHS UL1 TR000064
6 · The paper itself

Abstract

objectiveTo determine the effects of omitting meal time insulin on arterial stiffness in children with type 1 diabetes. RESEARCH DESIGN AND

methodsIn this prospective, randomized, crossover study, radial artery tonometry and augmentation index adjusted to heart rate 75 (AI

resultsWhen comparing change in AI

conclusionsArterial stiffness is decreased by premeal insulin in children with type 1 diabetes.

Indexed as

MealsAdolescentCardiovascular DiseasesChildCross-Over StudiesDiabetes Mellitus, Type 1Diabetic AngiopathiesDiabetic CardiomyopathiesDrug Administration ScheduleFemaleFloridaGlycated HemoglobinHumansHyperglycemiaHypoglycemic AgentsInsulinGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulinarterial stiffnessbolus insulinCVD riskmeal insulin

Identifiers

PMID27174580
PMCPMC6939859
OpenAlexW2353696605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.