Evidence map›Paper›PMID 27174197›Full record

ReviewJournal of neuro-oncology2016

Maximizing safe resection of low- and high-grade glioma.

Shawn L Hervey-Jumper, Mitchel S Berger

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05330559 (Fluorescence, Light-microscopy, Ultrasound Integrated / Intraoperative Diagnosis to MAXimise Resection), which is not on this map. Cited by 227 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
227citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05330559 unknown statusnot on this mapstarted 2022, after this paper: background citation

Fluorescence, Light-microscopy, Ultrasound Integrated / Intraoperative Diagnosis to MAXimise Resection

TypeobservationalSponsorFondazione I.R.C.C.S. Istituto Neurologico Carlo BestaRan2022 to 2024Enrolled50ConditionsPatients With Radiological, Clinical and Anamnestic Picture Compatible With a New Diagnosis of GlioblastomaArmsFluid MAX group
3 · Its place in the literature

Who cites it

227 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. SEOM-GEINO clinical guidelines for grade 2 gliomas (2023).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Guideline
  4. Pooled it
  5. Pooled it
  6. Pooled it
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  8. Pooled it
  9. Trial
  10. Review
  11. Article
  12. Article
  13. Blood derived extracellular vesicles in patients with glioblastoma: preliminary experience from a monoinstitutional series.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

167 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shawn L Hervey-JumperDepartment of Neurosurgery, University of Michigan, 1500 E. Medical Center Dr., Room 3552 TC, Ann Arbor, MI, 48109-5338, USA. herveyju@med.umich.edu.
Mitchel S BergerDepartment of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, M779, San Francisco, CA, 94143, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical resection plays a central role in the management of gliomas. In this study, we review the evidence in support of extent of resection to improve survival, symptom management, and time to malignant transformation in low- and high-grade gliomas, and summarize the findings from our literature search regarding the role of extent of resection and intraoperative practices to maximize safety. There is a growing body of evidence supporting improved overall survival, improved progression-free survival, and superior quality of life with greater extent of resection. Additionally, a better understanding of central nervous system plasticity allows for a staged approach to the surgical management of low- and intermediate-grade gliomas. A number of intraoperative techniques have been utilized to offer safer glioma surgery with greater extent of resection. Approaches such as awake brain tumor surgery can be safely performed with low failure rates and excellent long-term functional outcomes.

Indexed as

Neurosurgical ProceduresBrain NeoplasmsDisease-Free SurvivalGliomaHumansIntraoperative ComplicationsIntraoperative Neurophysiological MonitoringNeoplasm GradingNeuronal PlasticityNeuronavigationPreoperative Care5-ALAAwake craniotomyBrain mappingCNS plasticityCortical stimulation mappingExtent of resectionGlioblastomaGliomaHigh-grade gliomaIntraoperative MRILow-grade glioma

Identifiers

PMID27174197

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.