ArticleThe Journal of pediatrics2016
Nonlinear Relationship between Birth Weight and Visceral Fat in Adolescents.
Article in The Journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Infants With Low Birth Weight Have Larger Adipocytes During Early Childhood.Pediatric obesity · 2026Article
- Cardio-Metabolic Risk in Adults Born Preterm: A Narrative Review.Journal of clinical medicine · 2025Review
- Early life factors and variation in adult kidney function in the Swedish LifeGene cohort.Scientific reports · 2025Article
- Association between Marginally Low Birth Weight and Obesity-Related Outcomes and Indirect Effects via Attention-Deficit Hyperactivity Disorder and Abnormal Eating.Obesity facts · 2022Article
- What can we learn from β-cell failure biomarker application in diabetes in childhood? A systematic review.World journal of diabetes · 2021Article
- Adult-Onset Diseases in Low Birth Weight Infants: Association with Adipose Tissue Maldevelopment.Journal of atherosclerosis and thrombosis · 2020Review
- From conception to infancy - early risk factors for childhood obesity.Nature reviews. Endocrinology · 2019Review
- Developmental Programming of Body Composition: Update on Evidence and Mechanisms.Current diabetes reports · 2019Review
- Pregnancy phthalate metabolite concentrations and infant birth weight by gradations of maternal glucose tolerance.International journal of hygiene and environmental health · 2019Article
- Multi-behavioral obesogenic phenotypes among school-aged boys and girls along the birth weight continuum.PloS one · 2019Article
- The lifelong impact of fetal growth restriction on cardiac development.Pediatric research · 2018Article
- Birth weight is associated with dietary factors at the age of 6-8 years: the Physical Activity and Nutrition in Children (PANIC) study.Public health nutrition · 2018Article
- Overweight and Obesity in Schoolchildren: Hierarchical Analysis of Associated Demographic, Behavioral, and Biological Factors.Journal of obesity · 2018Article
- Birthweight and cardiometabolic risk patterns in multiracial children.International journal of obesity (2005) · 2018Article
- Birth weight and type 2 diabetes: A meta-analysis.Experimental and therapeutic medicine · 2017Article
- The initiation of metabolic inflammation in childhood obesity.The Journal of clinical investigation · 2017Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine the association of birth weight with abdominal fat distribution and markers known to increase risk for cardiovascular disease and type 2 diabetes in adolescents. STUDY
designIn 575 adolescents aged 14-18 years (52% female, 46% black), birth weight was obtained by parental recall. Fasting blood samples were measured for glucose, insulin, lipids, adiponectin, leptin, and C-reactive protein. Subcutaneous abdominal adipose tissue and visceral adipose tissue were assessed by magnetic resonance imaging.
resultsWhen we compared markers of cardiometabolic risk across tertiles of birth weight, adjusting for age, sex, race, Tanner stage, physical activity, socioeconomic status, and body mass index, there were significant U-shaped trends for homeostasis model assessment of insulin resistance, leptin, and visceral adipose tissue (all Pquadratic < .05). A significant linear downward trend across tertiles of birth weight was observed for triglycerides (Plinear = .03). There were no differences in fasting glucose, blood pressure, total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, adiponectin, C-reactive protein, or subcutaneous abdominal adipose tissue across tertiles of birth weight.
conclusionsOur data suggest that both low and high birth weights are associated with greater visceral adiposity and biomarkers implicated in insulin resistance and inflammation in adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.