ArticleMagnetic resonance in medicine2017
High quality three-dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla.
Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 52 citations in OpenAlex.
- Evaluating the effectiveness of distortion self-correction for CEST-EPI.Magnetic resonance in medicine · 2026Article
- MR-zero meets FLASH - controlling the transient signal decay in gradient- and RF-spoiled gradient echo sequences.Magnetic resonance in medicine · 2025Article
- Design Chemical Exchange Saturation Transfer Contrast Agents and Nanocarriers for Imaging Proton ExchangeACS nano · 2024Review
- Advances in diffuse glioma assessment: preoperative and postoperative applications of chemical exchange saturation transfer.Frontiers in neuroscience · 2024Review
- Biogenic Imaging Contrast Agents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Deep learning for dense Z-spectra reconstruction from CEST images at sparse frequency offsets.Frontiers in neuroscience · 2023Article
- An end-to-end AI-based framework for automated discovery of rapid CEST/MT MRI acquisition protocols and molecular parameter quantification (AutoCEST).Magnetic resonance in medicine · 2022Article
- Whole-brain steady-state CEST at 3 T using MR Multitasking.Magnetic resonance in medicine · 2022Article
- Quantification of Sodium Relaxation Times and Concentrations as Surrogates of Proteoglycan Content of Patellar CARTILAGE at 3T MRI.Diagnostics (Basel, Switzerland) · 2021Article
- In vitro and in vivo comparison of MRI chemical exchange saturation transfer (CEST) properties between native glucose and 3-O-Methyl-D-glucose in a murine tumor model.NMR in biomedicine · 2021Article
- 7 Tesla and Beyond: Advanced Methods and Clinical Applications in Magnetic Resonance Imaging.Investigative radiology · 2021Review
- Volumetric glutamate imaging (GluCEST) using 7T MRI can lateralize nonlesional temporal lobe epilepsy: A preliminary study.Brain and behavior · 2021Article
- Identification of Tumor-Specific MRI Biomarkers Using Machine Learning (ML).Diagnostics (Basel, Switzerland) · 2021Review
- Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: a feasibility study.Magma (New York, N.Y.) · 2021Article
- In vivo biochemical assessment of cartilage with gagCEST MRI: Correlation with cartilage properties.NMR in biomedicine · 2021Article
- A fast multislice sequence for 3D MRI-CEST pH imaging.Magnetic resonance in medicine · 2021Article
- Musculoskeletal MR Imaging Applications at Ultra-High (7T) Field Strength.Magnetic resonance imaging clinics of North America · 2021Review
- Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis.Journal of magnetic resonance imaging : JMRI · 2020Review
- Rapid volumetric gagCEST imaging of knee articular cartilage at 3 T: evaluation of improved dynamic range and an osteoarthritic population.NMR in biomedicine · 2020Article
- Computational technology for nasal cartilage-related clinical research and application.International journal of oral science · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeTo develop a new faster and higher quality three-dimensional (3D) gagCEST MRI technique for reliable quantification of glycosaminoglycan (GAG) present in the human knee cartilages.
methodsA new magnetization-prepared 3D gradient echo-based MRI pulse sequence has been designed to obtain the B
resultsThe gagCEST values of different compartments of knee cartilage are calculated using a newly developed technique for healthy subjects and a symptomatic knee cartilage degenerated subject. The effect of the acquired CEST saturation frequency offset step-size was investigated to establish the optimal step-size to obtain reproducible gagCEST maps. Our novel 3D gagCEST technique demonstrates markedly higher gagCEST contrast value than the previously reported 3D gagCEST studies. This study demonstrates the need for separate B
conclusionThe new technique provided high quality gagCEST maps with clearer visualization of different layers of knee cartilage with reproducible results. Magn Reson Med 77:1866-1873, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.