Evidence map›Paper›PMID 27173599›Full record

SynthesisGlobal public health

Towards 'reflexive epidemiology': Conflation of cisgender male and transgender women sex workers and implications for global understandings of HIV prevalence.

Amaya G Perez-Brumer, Catherine E Oldenburg, Sari L Reisner, Jesse L Clark, Richard G Parker

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Global public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Inclusion as illusion: erasing transgender women in research with MSM.Journal of the International AIDS Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amaya G Perez-Brumera Department of Sociomedical Sciences , Columbia Mailman School of Public Health , New York , NY , USA.
Catherine E Oldenburgb Department of Epidemiology , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Sari L Reisnerb Department of Epidemiology , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Jesse L Clarke Department of Medicine , David Geffen School of Medicine at UCLA , Los Angeles , CA , USA.
Richard G Parkera Department of Sociomedical Sciences , Columbia Mailman School of Public Health , New York , NY , USA.

Funding

HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
South American Program in HIV Prevention Research (SAPHIR)R25MH087222 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Karin Nielsen · 2011 to 2026
$3.9M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
GSH Training GrantT32HD049339 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jennifer S Hirsch · 2006 to 2026
$3.4M
TransPrEP: Social Network-Based PrEP Adherence for Transgender Women in PeruR34MH104072 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CLARK, JESSE LAWTON, MIMIAGA, MATTHEW JAMES · 2014 to 2016
$672k
NIAID NIH HHS T32 AI007535NICHD NIH HHS T32 HD049339NIDA NIH HHS T32 DA013911NIMH NIH HHS R25 MH083620NIMH NIH HHS R25 MH087222NIMH NIH HHS R34 MH104072
6 · The paper itself

Abstract

The HIV epidemic has had a widespread impact on global scientific and cultural discourses related to gender, sexuality, and identity. 'Male sex workers' have been identified as a 'key population' in the global HIV epidemic; however, there are methodological and conceptual challenges for defining inclusion and exclusion of transgender women within this group. To assess these potential implications, this study employs self-critique and reflection to grapple with the empiric and conceptual implications of shifting understandings of sexuality and gender within the externally re-created etic category of 'MSM' and 'transgender women' in epidemiologic HIV research. We conducted a sensitivity analysis of our previously published meta-analysis which aimed to identify the scope of peer-reviewed articles assessing HIV prevalence among male sex workers globally between 2004 and 2013. The inclusion of four studies previously excluded due to non-differentiation of cisgender male from transgender women participants (studies from Spain, Thailand, India, and Brazil: 421 total participants) increased the overall estimate of global HIV prevalence among 'men' who engage in sex work from 10.5% (95% CI 9.4-11.5%) to 10.8% (95% CI 9.8-11.8%). The combination of social science critique with empiric epidemiologic analysis represents a first step in defining and operationalising 'reflexive epidemiology'. Grounded in the context of sex work and HIV prevention, this paper highlights the multiplicity of genders and sexualities across a range of social and cultural settings, limitations of existing categories (i.e. 'MSM', 'transgender'), and their global implications for epidemiologic estimates of HIV prevalence.

Indexed as

Cross-Cultural ComparisonFemaleGender IdentityHIV InfectionsHomosexuality, MaleHumansMalePrevalenceRisk AssessmentSexualitySex WorkersTransgender PersonsVulnerable Populationsepidemiological categoriesHIVMen who have sex with mensex worktransgender women

Identifiers

PMID27173599
PMCPMC4931972

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.