Evidence map›Paper›PMID 27173521›Full record

ArticleDatabase : the journal of biological databases and curation2016

Mining chemical patents with an ensemble of open systems.

Robert Leaman, Chih-Hsuan Wei, Cherry Zou, Zhiyong Lu

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Extracting chemical-protein relations with ensembles of SVM and deep learning models.Database : the journal of biological databases and curation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert LeamanNational Center for Biotechnology Information (NCBI), 8600 Rockville Pike, Bethesda, MD, USA.
Chih-Hsuan WeiNational Center for Biotechnology Information (NCBI), 8600 Rockville Pike, Bethesda, MD, USA.
Cherry ZouNational Center for Biotechnology Information (NCBI), 8600 Rockville Pike, Bethesda, MD, USA Poolesville High School, 17501 W Wilard Rd, Poolesville, MD, USA.
Zhiyong LuNational Center for Biotechnology Information (NCBI), 8600 Rockville Pike, Bethesda, MD, USA zhiyong.lu@nih.gov.

Funding

Named Entity Recognition and Relationship Extraction in BiomedicineZIALM091813 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2013 to 2022
$13.4M
Intramural NIH HHS
6 · The paper itself

Abstract

The significant amount of medicinal chemistry information contained in patents makes them an attractive target for text mining. In this manuscript, we describe systems for named entity recognition (NER) of chemicals and genes/proteins in patents, using the CEMP (for chemicals) and GPRO (for genes/proteins) corpora provided by the CHEMDNER task at BioCreative V. Our chemical NER system is an ensemble of five open systems, including both versions of tmChem, our previous work on chemical NER. Their output is combined using a machine learning classification approach. Our chemical NER system obtained 0.8752 precision and 0.9129 recall, for 0.8937 f-score on the CEMP task. Our gene/protein NER system is an extension of our previous work for gene and protein NER, GNormPlus. This system obtained a performance of 0.8143 precision and 0.8141 recall, for 0.8137 f-score on the GPRO task. Both systems achieved the highest performance in their respective tasks at BioCreative V. We conclude that an ensemble of independently-created open systems is sufficiently diverse to significantly improve performance over any individual system, even when they use a similar approach.Database URL: http://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/tmTools/.

Indexed as

Databases, ChemicalDatabases, GeneticComputational BiologyData MiningInternetMachine LearningPatents as Topic

Identifiers

PMID27173521
PMCPMC4865327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.