Evidence map›Paper›PMID 27173407›Full record

SynthesisDeutsches Arzteblatt international2016

The Efficacy, Safety and Applications of Medical Hypnosis.

Winfried Häuser, Maria Hagl, Albrecht Schmierer, Ernil Hansen

4 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Deutsches Arzteblatt international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04024904 nacompletednot on this mapstarted 2018, after this paper: background citation

Virtual Reality Hypnosis Distraction Utility to Improve the Quality of Routine Procedure-related Pain During Preoperative Locoregional Anaesthesia

TypeinterventionalSponsorErasme University HospitalRan2018 to 2018Enrolled60ConditionsAnesthesiaArmsOncomfortTM device
NCT04133519 nacompletednot on this mapstarted 2019, after this paper: background citation

The Efficacy and Safety of IBS Digital Behavioral Treatment Study

TypeinterventionalSponsormetaMe HealthRan2019 to 2021Enrolled378ConditionsIrritable Bowel SyndromeArmsArm 1 - Active behavioral Treatment Arm (Regulora, Gut-Directed Hypnotherapy Software as a Medical Device - SaMD), Arm 2 - Active Comparator behavioral treatment arm (MR-1, Muscle Relaxation, Software as a Medical Device - SaMD)
NCT05413174 nacompletednot on this mapstarted 2022, after this paper: background citation

Contribution of Hypnosis in Guided Hepatic Biopsy

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2022 to 2023Enrolled70ConditionsUltrasound-guided Hepatic BiopsyArmsHypnoanalgésia
NCT07424209 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Hypnotic Communication in Reducing Emotional Distress and Improving Patient Experience During Elective Coronary Angiography: A Monocentric Randomized Controlled Trial

TypeinterventionalSponsorUniversità degli Studi del Piemonte Orientale Amedeo AvogadroRan2025 to 2027Enrolled306ConditionsPsychological Distress, Pain, AnxietyArmsHypnotic Communication
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Hypnosis Intervention Effects on Sleep Outcomes: A Systematic Review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Pooled it
  3. Virtual reality hypnosis during protective isolation: a parallel group randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  4. Trial
  5. Trial
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  7. Trial
  8. Article
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  13. Review
  14. Brain Mechanisms of Hypnosis.Brain sciences · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Winfried HäuserDepartment of Internal Medicine I, Klinikum Saarbrücken, Saarbrücken and Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Münich, Department of Psychology, Ludwig-Maximilians-Universität München, Münich, Dental Practice Schmierer & Kratzenstein, Stuttgart, Department of Anesthesiology, Universitätsklinikum Regensburg.
Maria Hagl
Albrecht Schmierer
Ernil Hansen
Klinikum rechts der Isar · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy and safety of hypnotic techniques in somatic medicine, known as medical hypnosis, have not been supported to date by adequate scientific evidence.

methodsWe systematically reviewed meta-analyses of randomized controlled trials (RCTs) of medical hypnosis. Relevant publications (January 2005 to June 2015) were sought in the Cochrane databases CDSR and DARE, and in PubMed. Meta-analyses involving at least 400 patients were included in the present analysis. Their methodological quality was assessed with AMSTAR (A Measurement Tool to Assess Systematic Reviews). An additional search was carried out in the CENTRAL and PubMed databases for RCTs of waking suggestion (therapeutic suggestion without formal trance induction) in somatic medicine.

resultsOut of the 391 publications retrieved, five were reports of metaanalyses that met our inclusion criteria. One of these meta-analyses was of high methodological quality; three were of moderate quality, and one was of poor quality. Hypnosis was superior to controls with respect to the reduction of pain and emotional stress during medical interventions (34 RCTs, 2597 patients) as well as the reduction of irritable bowel symptoms (8 RCTs, 464 patients). Two meta-analyses revealed no differences between hypnosis and control treatment with respect to the side effects and safety of treatment. The effect size of hypnosis on emotional stress during medical interventions was low in one meta-analysis, moderate in one, and high in one. The effect size on pain during medical interventions was low. Five RCTs indicated that waking suggestion is effective in medical procedures.

conclusionMedical hypnosis is a safe and effective complementary technique for use in medical procedures and in the treatment of irritable bowel syndrome. Waking suggestions can be a component of effective doctor-patient communication in routine clinical situations.

Indexed as

AdultAgedEvidence-Based MedicineFemaleHumansHypnosisMaleMiddle AgedPainPatient SafetyPrevalenceRisk FactorsStress, PsychologicalTreatment OutcomeYoung Adult

Identifiers

PMID27173407
PMCPMC4873672
OpenAlexW2423494444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.