ArticleScientific reports2016
A high definition Mueller polarimetric endoscope for tissue characterisation.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Polarizer-assisted pupillometry through closed eyelids, overcoming pupil position dependence.Journal of biomedical optics · 2026Article
- Diffraction order-engineered polarization-dependent silicon nano-antennas metagrating for compact subtissue Mueller microscopy.Nanophotonics (Berlin, Germany) · 2025Article
- Multi-exposure speckle imaging through an optical fiber bundle.Journal of biomedical optics · 2025Article
- Label-free distinction of implant infection-associated bacterial biofilms by Mueller matrix polarimetry.Journal of biomedical optics · 2025Article
- Probing the Influence of Specular Reflection and Overexposure on Backscattering Mueller Matrix Polarimetry for Tissue Imaging and Sensing.Biosensors · 2025Article
- Polarimetry through a flexible imaging fiber bundle with a pixelated polarizer.Biomedical optics express · 2025Article
- Mueller matrix analysis of a biologically sourced engineered tissue construct as polarimetric phantom.Journal of biomedical optics · 2024Article
- Computational Polarization Imaging In Vivo through Surgical Smoke Using Refined Polarization Difference.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Characterization and classification of ductal carcinoma tissue using four channel based stokes-mueller polarimetry and machine learning.Lasers in medical science · 2024Article
- Influence of signal-to-noise ratio on DoLP and AoP measurements during reflectance-mode division-of-focal plane Stokes polarimetry of biological tissues.Biomedical optics express · 2024Article
- Analysis of polarization features of human breast cancer tissue by Mueller matrix visualization.Journal of biomedical optics · 2024Article
- Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging.Journal of biomedical optics · 2024Article
- Mechanical stability of polarization signatures in biological tissue characterization.Biomedical optics express · 2024Article
- Ptychographic lens-less birefringence microscopy using a mask-modulated polarization image sensor.Scientific reports · 2023Article
- Evaluation of a polarization-enhanced laparoscopy prototype for improved intra-operative visualization of peritoneal metastases.Scientific reports · 2023Article
- Surgical polarimetric endoscopy for the detection of laryngeal cancer.Nature biomedical engineering · 2023Article
- Optical anisotropy composition of benign and malignant prostate tissues revealed by Mueller-matrix imaging.Biomedical optics express · 2022Article
- Assessment of tissue pathology using optical polarimetry.Lasers in medical science · 2022Article
- Polarization-based smoke removal method for surgical images.Biomedical optics express · 2022Article
- Stokes Dynamic Polarimeter for Non-Organic and Organic Samples Characterization.Sensors (Basel, Switzerland) · 2022Article
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Authors and funding
2 authors.
Funding
Abstract
The contrast mechanism of medical endoscopy is mainly based on metrics of optical intensity and wavelength. As another fundamental property of light, polarization can not only reveal tissue scattering and absorption information from a different perspective, but can also provide insight into directional tissue birefringence properties to monitor pathological changes in collagen and elastin. Here we demonstrate a low cost wide field high definition Mueller polarimetric endoscope with minimal alterations to a rigid endoscope. We show that this novel endoscopic imaging modality is able to provide a number of image contrast mechanisms besides traditional unpolarized radiation intensity, including linear depolarization, circular depolarization, cross-polarization, directional birefringence and dichroism. This enhances tissue features of interest, and additionally reveals tissue micro-structure and composition, which is of central importance for tissue diagnosis and image guidance for surgery. The potential applications of the Mueller polarimetric endoscope include wide field early epithelial cancer diagnosis, surgical margin detection and energy-based tissue fusion monitoring, and could further benefit a wide range of endoscopic investigations through intra-operative guidance.
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