ArticleJournal of the American College of Cardiology2016
Quality of Life of Adults With Congenital Heart Disease in 15 Countries: Evaluating Country-Specific Characteristics.
Article in Journal of the American College of Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychological interventions for depression in adolescent and adult congenital heart disease.The Cochrane database of systematic reviews · 2023Pooled it
- Right ventricular function, exercise capacity and quality of life in adults with congenital heart disease and the effect of a home-based exercise program.International journal of cardiology. Congenital heart disease · 2026Article
- Developmental Systems Cardiology II: Implementing a Lifespan Model for Clinical Practice.Pediatric cardiology · 2026Article
- US Adult Congenital Heart Disease Fellowship Match Outcomes in the Context of the Global ACHD Workforce.Pediatric cardiology · 2026Review
- Assessing Quality of Life in Genetic Cardiomyopathies: A Scoping Review.International journal of environmental research and public health · 2026Article
- The impact of psychosocial factors on secondary hyperparathyroidism and vitamin D deficiency in adults with congenital heart disease-the CHD-HYPER study.Frontiers in nutrition · 2026Article
- Quality of Life in Adults with Congenital Heart Disease: Insights from a Tertiary Centre.Journal of clinical medicine · 2025Article
- Prevalence and Predictors of Neurocognitive Dysfunction in Adults With Congenital Heart Disease: Results From MINDS-ACHD.Journal of the American College of Cardiology · 2025Article
- Efficacy of Magnetic Resonance Elastography in Fontan-Associated Liver Disease.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Fatigue in adults with congenital heart disease aged over 40 years.International journal of cardiology. Congenital heart disease · 2025Article
- Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries.Heart (British Cardiac Society) · 2025Article
- Psychiatric and Psychological Implications of Congenital Heart Disease.Journal of clinical medicine · 2025Review
- Stable Longitudinal Quality of Life in the SERVE Trial Among Adults With Transposition of the Great Arteries and a Systemic Right Ventricle.CJC pediatric and congenital heart disease · 2025Article
- Educational Attainment and Employment Status of Adults Living With Congenital Heart Disease in the United States, CH STRONG 2016-2019.Birth defects research · 2025Article
- Quality of life in people with syndromic heritable thoracic aortic disease and their relatives: a qualitative interview based study.Orphanet journal of rare diseases · 2025Article
- Patient-Reported Outcome-Based, Comprehensive Assessment of Quality of Life of Adults with Congenital Heart Disease in India.Global heart · 2025Article
- Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.Frontiers in pediatrics · 2025Article
- Determinants of life satisfaction in adolescents with congenital or acquired heart disease: a nationwide cross-sectional study.BMC public health · 2024Article
- Quality of Life and Well-Being in Adults With Fontan Physiology: Findings From the Australian and New Zealand Fontan Registry Quality of Life Study.Journal of the American Heart Association · 2024Article
- Health-Related Quality of Life and Its Association With Outcomes in Adults With Congenital Heart Disease and Heart Failure: Insight From FRESH-ACHD Registry.Journal of the American Heart Association · 2023Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
29 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeasuring quality of life (QOL) is fundamental to understanding the impact of disease and treatment on patients' lives.
objectivesThis study aimed to explore QOL in an international sample of adults with congenital heart disease (CHD), the association between patient characteristics and QOL, and international variation in QOL and its relationship to country-specific characteristics.
methodsWe enrolled 4,028 adults with CHD from 15 countries. QOL was assessed using a linear analog scale (LAS) (0 to 100) and the Satisfaction with Life Scale (SWLS) (5 to 35). Patient characteristics included sex, age, marital status, educational level, employment status, CHD complexity, and patient-reported New York Heart Association (NYHA) functional class. Country-specific characteristics included general happiness and 6 cultural dimensions. Linear mixed models were applied.
resultsMedian QOL was 80 on the LAS and 27 on the SWLS. Older age, lack of employment, no marriage history, and worse NYHA functional class were associated with lower QOL (p < 0.001). Patients from Australia had the highest QOL (LAS: 82) and patients from Japan the lowest (LAS: 72). Happiness scores and cultural dimensions were not associated with variation in QOL after adjustment for patient characteristics and explained only an additional 0.1% of the variance above and beyond patient characteristics (p = 0.56).
conclusionsThis large-scale, international study found that overall QOL in adults with CHD was generally good. Variation in QOL was related to patient characteristics but not country-specific characteristics. Hence, patients at risk for poorer QOL can be identified using uniform criteria. General principles for designing interventions to improve QOL can be developed.
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