Evidence map›Paper›PMID 27172372›Full record

ReviewHuman vaccines & immunotherapeutics2016

Is HPV vaccination in pregnancy safe?

Ulla Bonde, Jan Stener Joergensen, Ronald F Lamont, Ole Mogensen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Maternal vaccination: a review of current evidence and recommendations.American journal of obstetrics and gynecology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ulla Bondea Department of Gynecology and Obstetrics , Odense University Hospital , Odense , Denmark.
Jan Stener Joergensena Department of Gynecology and Obstetrics , Odense University Hospital , Odense , Denmark.
Ronald F Lamonta Department of Gynecology and Obstetrics , Odense University Hospital , Odense , Denmark.
Ole Mogensena Department of Gynecology and Obstetrics , Odense University Hospital , Odense , Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Millions of doses of HPV vaccine have been administered globally. Inadvertent administration of HPV vaccine during pregnancy occurs given that the main recipients of the vaccine are fertile young women, who might be unaware of their pregnancy at the time of their vaccination. To investigate the subject of HPV vaccine and pregnancy , the databases of PubMed and Embase were searched to find the relevant literature published in English within the last 10 y. Most of the evidence pertaining to fetal adverse events following HPV vaccination relates to spontaneous miscarriage. None of the relevant studies found any significantly increased rate of spontaneous abortion in the overall analyses. There was no indication of other HPV vaccine-associated adverse events in pregnancy or immediately post-conception.

Indexed as

Abortion, SpontaneousDrug-Related Side Effects and Adverse ReactionsFemaleHumansPapillomavirus InfectionsPapillomavirus VaccinesPregnancyVaccinationPapillomavirus Vaccinesadverse eventsHPVpregnancyspontaneous abortionvaccine

Identifiers

PMID27172372
PMCPMC4994723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.