Evidence map›Paper›PMID 27171853›Full record

ArticleOcular oncology and pathology2015

Conjunctival Intraepithelial Neoplasia with Mucoepidermoid Differentiation: A Case Report of a Subtle Lesion.

Madhura G Joag, Anita Gupta, Anat Galor, Sander R Dubovy, Jose Antonio Bermudez-Magner, Jianhua Wang, Carol L Karp

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Ocular oncology and pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Madhura G JoagBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA.
Anita GuptaBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA.
Anat GalorBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA; Miami Veterans Affairs Medical Center, Miami, Fla., USA.
Sander R DubovyBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA; Florida Lions Eye Bank, Ocular Pathology Laboratory, Miami, Fla., USA.
Jose Antonio Bermudez-MagnerBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA; Florida Lions Eye Bank, Ocular Pathology Laboratory, Miami, Fla., USA.
Jianhua WangBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA.
Carol L KarpBascom Palmer Eye Institute, University of Miami, Miami, Fla., USA.
University of Miami · USMinnesota Lions Eye Bank · USMiami VA Healthcare System · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
NEI NIH HHS P30 EY014801
6 · The paper itself

Abstract

objectiveTo describe the clinical presentation, diagnostic imaging, and treatment options of conjunctival intraepithelial neoplasia (CIN) with mucoepidermoid differentiation, an in situ stage of mucoepidermoid carcinoma of the conjunctiva (MCC).

resultsWe report the case of an 86-year-old man presenting with a subtle limbal lesion that had only mild erythema and elevation. Based on a few atypical clinical features and an abnormal ultrahigh-resolution optical coherence tomography (UHR OCT), an incisional biopsy was performed revealing CIN with mucoepidermoid differentiation. Treatment involved aggressive surgical excision. No evidence of recurrence was noted in the 5 years of follow-up.

conclusionMCC is an aggressive tumor that has a tendency to be invasive and recur after treatment. Therefore, early diagnosis and treatment is critical. CIN with mucoepidermoid differentiation may represent the earliest stage of MCC. It can present subtly, with a clinical resemblance to benign and less aggressive ocular surface lesions. Imaging with UHR OCT may be helpful to detect early neoplasia. A high level of suspicion must be maintained when evaluating potential ocular surface tumors.

Indexed as

Conjunctival intraepithelial neoplasiaImagingMucoepidermoid differentiationNeoplasiaOptical coherence tomography

Identifiers

PMID27171853
PMCPMC4847679
OpenAlexW917136612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.