Evidence map›Paper›PMID 27171742›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Illness Perceptions, Medication Beliefs, and Adherence to Antiretrovirals and Medications for Comorbidities in Adults With HIV Infection and Hypertension or Chronic Kidney Disease.

Jeffrey J Weiss, Ioannis Konstantinidis, Anna Boueilh, Daniel S Fierer, Donald Gardenier, Mark G Barber, Tony Kang, Anna Kress, Katherine Ericson, Marlene C Lira and 4 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Observational
  7. Observational
  8. Article
  9. Article
  10. People Living With HIV: Implications for Rehabilitation Nurses.Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jeffrey J Weiss*Division of General Internal Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; †Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; ‡Department of Nephrology-Transplantation-Dialysis, Pellegrin Hospital, Bordeaux, France; §Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; ‖School of Medicine, University of Connecticut, Farmington, CT; ¶Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA; #Department of Internal Medicine, Columbia University Medical Center, New York-Presbyterian Hospital, New York, NY; **College of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; ††Clinical Addiction Research and Education (CARE) Unit, General Internal Medicine, Medicine, Boston Medical Center, Boston, MA; ‡‡School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland; §§Department of Family Medicine and Community Health, Perelman School of Medicine, Philadelphia, PA; and ‖‖Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Ioannis Konstantinidis
Anna Boueilh
Daniel S Fierer
Donald Gardenier
Mark G Barber
Tony Kang
Anna Kress
Katherine Ericson
Marlene C Lira
Marina P Yostos
Hillary R Bogner
Juan P Wisnivesky
Christina M Wyatt

Funding

Determinants of Medication Adherence in HIV-Infected Adults with HypertensionR21NR012648 · NINR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WEISS, JEFFREY J · 2010 to 2011
$464k
NINR NIH HHS R21 NR012648
6 · The paper itself

Abstract

backgroundMortality in patients with HIV infection is increasingly due to comorbid medical conditions. Research on how adherence to medications for comorbidities relates to antiretroviral (ARV) medication adherence and how interrelations between illness perceptions and medication beliefs about HIV and comorbidities affect medication adherence is needed to inform adherence interventions.

methodsHIV-infected adults with hypertension (HTN) (n = 151) or chronic kidney disease (CKD; n = 41) were recruited from ambulatory practices at an academic medical center. Illness perceptions and medication beliefs about HIV and HTN or CKD were assessed and adherence to one ARV medication and one medication for either HTN or CKD was electronically monitored for 10 weeks.

resultsRates of taking, dosing, and timing adherence to ARV medication did not differ from adherence to medication for HTN or CKD, with the exception that patients were more adherent to the timing of their ARV (78%) than to the timing of their antihypertensive (68%; P = 0.01). Patients viewed HIV as better understood, more chronic, having more negative consequences, and eliciting more emotions, compared with HTN. Patients viewed ARVs as more necessary than medication for HTN or CKD. Having a realistic view of the efficacy of ARVs (r = -0.20; P < 0.05) and a high level of perceived HIV understanding (r = 0.21; P < 0.05) correlated with better ARV adherence.

conclusionsPatients with HIV showed similar rates of adherence to ARVs as to medications for comorbidities, despite perceiving HIV as more threatening and ARVs as more important. This can be used in adapting existing interventions for ARV adherence to encompass adherence to medications for comorbid conditions.

Indexed as

Health Knowledge, Attitudes, PracticeMedication AdherenceAnti-HIV AgentsAntihypertensive AgentsFemaleHIV InfectionsHumansHypertensionMaleMiddle AgedRenal Insufficiency, ChronicViral LoadAnti-HIV AgentsAntihypertensive Agents

Identifiers

PMID27171742
PMCPMC5085852

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.