ArticlePloS one2016
Molecular Characterization of Methicillin Resistant Staphylococcus aureus Strains Isolated from Intensive Care Units in Iran: ST22-SCCmec IV/t790 Emerges as the Major Clone.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Methicillin-ResistantToxins · 2020Pooled it
- Draft genome sequence of a methicillin-resistantMicrobiology resource announcements · 2026Article
- Virulence Gene Profile and Antimicrobial Susceptibility ofMicroorganisms · 2026Article
- Molecular typing of PVL-positive Staphylococcus aureus isolates from Lithuania and genome sequencing of a local outbreak strain.Scientific reports · 2026Article
- Prevalence, Antimicrobial Resistance Profiles, and Molecular Characteristics of Methicillin-ResistantPathogens (Basel, Switzerland) · 2026Article
- Genetic diversity ofJournal of water and health · 2026Article
- Molecular Characterization of Clinical Isolates of Methicillin-ResistantPathogens (Basel, Switzerland) · 2025Article
- Rapid Detection of Panton-Valentine Leukocidin Production in Clinical Isolates ofPathogens (Basel, Switzerland) · 2025Article
- Genotyping of Clinical Samples of Methicillin-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Unveiling the Genetic Landscape ofInternational journal of microbiology · 2025Article
- Phenotypic and genotypic characterization ofHeliyon · 2024Article
- Characterisation of PVL-PositiveAntibiotics (Basel, Switzerland) · 2024Article
- Predictors for multidrug-resistant organisms (MDROs) carriage in haemodialysis patients.Journal of family medicine and primary care · 2024Article
- Emerging Challenges inAdvances in medicine · 2023Article
- Identification of major sequence types among aminoglycoside resistantIranian journal of microbiology · 2022Article
- Antimicrobial Resistance and Clonal Lineages ofMicroorganisms · 2022Article
- Determination of Virulence Factors and Resistance Profile of Methicillin-ResistantBioMed research international · 2022Article
- Diversity of clonal complex 22 methicillin-resistantFrontiers in microbiology · 2022Article
- Clonal Diversity and Epidemiological Characteristics of ST239-MRSA Strains.Frontiers in cellular and infection microbiology · 2022Article
- Mupirocin-ResistantBioMed research international · 2022Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different patient populations is a major public health concern. This study determined the prevalence and distribution of circulating molecular types of MRSA in hospitalized patients in ICU of hospitals in Tehran. MATERIALS AND
methodsA total of 70 MRSA isolates were collected from patients in eight hospitals. Antimicrobial resistance patterns were determined using the disk diffusion method. The presence of toxin encoding genes and the vancomycin resistance gene were determined by PCR. The MRSA isolates were further analyzed using multi-locus sequence, spa, SCCmec, and agr typing.
resultsThe MRSA prevalence was 93.3%. Antimicrobial susceptibility testing revealed a high resistance rate (97.1%) to ampicillin and penicillin. The rate of resistance to the majority of antibiotics tested was 30% to 71.4%. Two isolates belonging to the ST22-SCCmec IV/t790 clone (MIC ≥ 8 μg/ml) had intermediate resistance to vancomycin. The majority of MRSA isolates (24.3%) were associated with the ST22-SCCmec IV/t790 clone; the other MRSA clones were ST859-SCCmec IV/t969 (18.6%), ST239-SCCmec III/t037 (17.1%), and ST291-SCCmec IV/t030 (8.6%).
conclusionsThe circulating MRSA strains in Iranian hospitals were genetically diverse with a relatively high prevalence of the ST22-SCCmec IV/t790 clone. These findings support the need for future surveillance studies on MRSA to better elucidate the distribution of existing MRSA clones and detect emergence of new MRSA clones.
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