Evidence map›Paper›PMID 27171205›Full record

ArticleOcular oncology and pathology2015

Orbital Paraganglioma and Succinate Dehydrogenase Staining for Genetic Testing Triage and Prognosis.

Cesar M Salinas-La Rosa

Open access · bronzeAbstract read
In one paragraph

Article in Ocular oncology and pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Orbital Paraganglioma: A Systematic Review.Journal of neurological surgery. Part B, Skull base · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Cesar M Salinas-La RosaDepartment of Anatomical Pathology, St Vincent's Hospital, Melbourne. Vic., Australia.
St Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the studyTo describe the rare occurrence of a paraganglioma in the orbit and how to triage for genetic testing and assess the prognosis with succinate dehydrogenase subunit B (SDHB) immunohistochemical staining.

methodCase report. PROCEDURES: A 47-year-old 'healthy' male presented with painless exophthalmos and diplopia secondary to an infraorbital tumour mass.

resultsThe orbital biopsy was diagnosed as paraganglioma with positive staining with SDHB.

conclusionThe rarity of an orbital paraganglioma was followed by the clinical search for a possible occult extraorbital primary paraganglioma. SDHB staining helped in the triage for genetic testing and gave an idea about the prognosis for this tumour.

Indexed as

Familial syndromeOrbitParagangliomaSuccinate dehydrogenase immunohistochemical stain

Identifiers

PMID27171205
PMCPMC4847686
OpenAlexW2209163638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.