ArticlePloS one2016
The Role of Body Fat and Fat Distribution in Hypertension Risk in Urban Black South African Women.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Inulin Supplementation Reduces Systolic Blood Pressure in Women with Breast Cancer Undergoing Neoadjuvant Chemotherapy.Cardiovascular therapeutics · 2019Trial
- Body composition displays expected and unexpected contributions to blood pressure and glycemia in young South African women.BMJ open diabetes research & care · 2026Article
- Risk stratification of hypertension in South Africa: a systematic review with meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- Risk factors of hypertension in South Africa: A systematic review and meta-analysis to inform the development of a clinical prediction model.Health SA = SA Gesondheid · 2026Article
- Machine Learning Approach for Predicting Hypertension Based on Body Composition in South Korean Adults.Bioengineering (Basel, Switzerland) · 2024Article
- Physical activity alters the effect of genetic determinants of adiposity on hypertension among individuals of European ancestry in the UKB.Scandinavian journal of medicine & science in sports · 2024Article
- Cardiometabolic Health in Pregnancy and Postpartum: Findings From a Prospective Cohort Study in South Africa.Open forum infectious diseases · 2024Article
- The association of body composition and fat distribution with hypertension in community-dwelling older adults: the Bushehr Elderly Health (BEH) program.BMC public health · 2023Article
- Blood pressure control in hypertensive patients attending a rural community health centre in Gauteng Province, South Africa: A cross-sectional study.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- A Matter of Fat: Body Fat Distribution and Cardiometabolic Disease in Africa.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Body composition of the upper limb associated with hypertension, hypercholesterolemia, and diabetes.Frontiers in endocrinology · 2022Article
- Different Indicators of Adiposity and Fat Distribution and Cardiometabolic Risk Factors in Patients with Type 2 Diabetes.Obesity (Silver Spring, Md.) · 2021Article
- Chronic Kidney Disease Modifies The Relationship Between Body Fat Distribution and Blood Pressure: A Cross-Sectional Analysis.International journal of nephrology and renovascular disease · 2020Article
- Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008-2010.PloS one · 2020Article
- Prognostic value of adiposity indices for hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Body fat percentage, obesity, and their relation to the incidental risk of hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Fat redistribution and accumulation of visceral adipose tissue predicts type 2 diabetes risk in middle-aged black South African women: a 13-year longitudinal study.Nutrition & diabetes · 2019Article
- Different adiposity indices and their association with blood pressure and hypertension in middle-aged urban black South African men and women: findings from the AWI-GEN South African Soweto Site.BMC public health · 2018Article
- Using Anthropometric Indicator to Identify Hypertension in Adolescents: A Study in Sarawak, Malaysia.International journal of hypertension · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Developing countries are disproportionately affected by hypertension, with Black women being at greater risk, possibly due to differences in body fat distribution. The objectives of this study were: (1) To examine how different measures of body composition are associated with blood pressure (BP) and incident hypertension; (2) to determine the association between baseline or change in body composition, and hypertension; and (3) to determine which body composition measure best predicts hypertension in Black South African women. The sample comprised 478 non-hypertensive women, aged 29-53 years. Body fat and BP were assessed at baseline and 8.3 years later. Body composition was assessed using dual-energy X-ray absorptiometry (DXA) (n = 273) and anthropometry. Hypertension was diagnosed based on a systolic/diastolic BP ≥140/90 mmHg, or medication use at follow-up. All body composition measures increased (p<0.0001) between baseline and follow-up. SBP and DBP increased by ≥20%, resulting in a 57.1% cumulative incidence of hypertension. Both DXA- and anthropometric-derived measures of body composition were significantly associated with BP, explaining 3-5% of the variance. Baseline BP was the most important predictor of hypertension (adjusted OR: 98-123%). Measures of central adiposity were associated with greater odds (50-65%) of hypertension than total adiposity (44-45%). Only change in anthropometric-derived central fat mass predicted hypertension (adjusted OR: 32-40%). This study highlights that body composition is not a major determinant of hypertension in the sample of black African women. DXA measures of body composition do not add to hypertension prediction beyond anthropometry, which is especially relevant for African populations globally, taking into account the severely resource limited setting found in these communities.
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Registered trials
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