ArticleIEEE journal of translational engineering in health and medicine2013
Design and Characterization of an Osmotic Sensor for the Detection of Events Associated with Dehydration and Overhydration.
Article in IEEE journal of translational engineering in health and medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Biosensor-Enhanced Organ-on-a-Chip Models for Investigating Glioblastoma Tumor Microenvironment Dynamics.Sensors (Basel, Switzerland) · 2024Review
- Advances in Non-Electrochemical Sensing of Human Sweat Biomarkers: From Sweat Sampling to Signal Reading.Biosensors · 2023Review
- Integrated biosensors for monitoring microphysiological systems.Lab on a chip · 2022Review
- A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification.Microsystems & nanoengineering · 2019Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The level of hydration in the human body is carefully adjusted to control the electrolyte balance that governs the biochemical processes that sustain life. An electrolyte deficiency caused by de- or overhydration will not only limit human performance, but can also lead to serious health problems and death if left untreated. Because humans can withstand a change in hydration of only [Formula: see text], frequent monitoring should be performed in risk groups. This paper presents an osmotic hydration sensor that can record the level of hydration as a function of osmotic pressure in phosphate buffered saline or sodium-chloride solutions that simulate the interstitial fluid in the body. The osmotic pressure is recorded with the aid of an ion-exchange membrane that facilitates the migration of water and cations, in favor of reverse osmosis or gas separation membranes. The hydration sensor is designed to be coupled to an inductively powered readout circuit designed for integration in a micro-implant that has previously been shown to consume only 76 [Formula: see text] of power. The dynamic range spans a state of serious overhydration (220 [Formula: see text]) to a serious state of dehydration (340 [Formula: see text]) with a response time of [Formula: see text] (for a variation of hydration of 20%).
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