ArticleProceedings. Biological sciences2016
Epidemiological analysis of the Eyam plague outbreak of 1665-1666.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- A step forward toward solving the main mysteries in the history of plague?Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Differential word expression analyses highlight plague dynamics during the second pandemic.Royal Society open science · 2022Article
- Differential mortality of infectious disease in Italian polities: COVID-19, past plague epidemics, and currently endemic respiratory disease.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Article
- Assessing the origins of the European Plagues following the Black Death: A synthesis of genomic, historical, and ecological information.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The influence of temperature on the seasonality of historical plague outbreaks.Proceedings. Biological sciences · 2021Article
- Protection against severe infectious disease in the past.Pathogens and global health · 2021Review
- How epidemics end.Centaurus; international magazine of the history of science and medicine · 2021Article
- Plague Transmission from Corpses and Carcasses.Emerging infectious diseases · 2021Review
- COVID-19 and the ethics of quarantine: a lesson from the Eyam plague.Medicine, health care, and philosophy · 2020Article
- Will an outbreak exceed available resources for control? Estimating the risk from invading pathogens using practical definitions of a severe epidemic.Journal of the Royal Society, Interface · 2020Article
- A digital reconstruction of the 1630-1631 large plague outbreak in Venice.Scientific reports · 2020Article
- Article
- Mortality and demographic recovery in early post-black death epidemics: Role of recent emigrants in medieval Dijon.PloS one · 2020Article
- Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes.Nature communications · 2019Article
- The 'light touch' of the Black Death in the Southern Netherlands: an urban trick?The Economic history review · 2019Article
- Epidemiology of Plague: Problems with the Use of Mathematical Epidemiological Models in Plague Research and the Question of Transmission by Human Fleas and Lice.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019Review
- Epidemiology of a bubonic plague outbreak in Glasgow, Scotland in 1900.Royal Society open science · 2019Article
- A critical review of anthropological studies on skeletons from European plague pits of different epochs.Scientific reports · 2018Review
- Human ectoparasites and the spread of plague in Europe during the Second Pandemic.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Plague, caused by the bacterium Yersinia pestis, is one of the deadliest infectious diseases in human history, and still causes worrying outbreaks in Africa and South America. Despite the historical and current importance of plague, several questions remain unanswered concerning its transmission routes and infection risk factors. The plague outbreak that started in September 1665 in the Derbyshire village of Eyam claimed 257 lives over 14 months, wiping out entire families. Since previous attempts at modelling the Eyam plague, new data have been unearthed from parish records revealing a much more complete record of the disease. Using a stochastic compartmental model and Bayesian analytical methods, we found that both rodent-to-human and human-to-human transmission played an important role in spreading the infection, and that they accounted, respectively, for a quarter and three-quarters of all infections, with a statistically significant seasonality effect. We also found that the force of infection was stronger for infectious individuals living in the same household compared with the rest of the village. Poverty significantly increased the risk of disease, whereas adulthood decreased the risk. These results on the Eyam outbreak contribute to the current debate on the relative importance of plague transmission routes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.