ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2016
Optical coherence tomography measurements in compressive optic neuropathy associated with dysthyroid orbitopathy.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- OCT and OCTA in dysthyroid optic neuropathy: a systematic review and meta-analysis.BMJ open ophthalmology · 2023Pooled it
- Electrophysiological Studies in Thyroid Associated Orbitopathy: A Systematic Review.Scientific reports · 2017Pooled it
- Retinal and Choroidal Alterations in Thyroid-Associated Ophthalmopathy: A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Evaluation of retinal nerve fiber and ganglion cell layer abnormalities using optical coherence tomography in thyroid-associated orbitopathy.Arquivos brasileiros de oftalmologia · 2025Article
- Utility of isolated-check visual evoked potential technique in dysthyroid optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Chromatic visual evoked potentials identify optic nerve dysfunction in patients with Graves' orbitopathy.International ophthalmology · 2022Article
- Peripapillary structural and microvascular alterations in early dysthyroid optic neuropathy.Eye and vision (London, England) · 2022Article
- Functional and Morphological Changes in the Visual Pathway in Patients with Graves' Orbitopathy.Journal of clinical medicine · 2022Article
- Insights into Current Management Strategies for Dysthyroid Optic Neuropathy: A Review.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- The Changes in Optic Nerve after Orbital Decompression Surgery for Thyroid Eye Disease and Case Reports of Ischemic Optic Neuropathy.BioMed research international · 2022Article
- Retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after orbital decompression for dysthyroid optic neuropathy.International ophthalmology · 2021Article
- Different damage patterns of retinal nerve fiber layer and ganglion cell-inner plexiform layer between early glaucoma and non-glaucomatous optic neuropathy.International journal of ophthalmology · 2020Article
- Reduced macular inner retinal thickness and microvascular density in the early stage of patients with dysthyroid optic neuropathy.Eye and vision (London, England) · 2020Article
- Correlation of peripapillary nerve fiber layer thickness with visual outcomes after decompression surgery in subclinical and clinical thyroid-related compressive optic neuropathy.Journal of current ophthalmology · 2019Article
- Effect of orbital decompression on dysthyroid optic neuropathy: A retrospective case series.Medicine · 2019Observational
- Changes in optical coherence tomography measurements after orbital wall decompression in dysthyroid optic neuropathy.Eye (London, England) · 2018Article
- Changes in retinal nerve fiber layer, ganglion cell complex, and ganglion cell layer thickness in thyroid eye disease: A systematic review.Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of the study was to assess the influence of optic nerve compression on the peripapillary retinal nerve fiber layer (RNFL) thickness in eyes with acute and chronic dysthyroid optic neuropathy (DON).
methodsPatients with DON and healthy control subjects underwent peripapillary optical coherence tomography (OCT) scanning with the Cirrus HD-OCT. Patients were classified as acute (within 6 months from the onset of DON) versus chronic (6 months or more from the onset of DON) DON. The thickness of peripapillary RNFL was compared between eyes with acute and chronic DON and control eyes. Baseline factors associated with visual acuity at the last visit were also analyzed.
resultsThe mean temporal peripapillary RNFL thickness was thinnest in chronic DON at 66 ± 12 μm compared to 76 ± 8 μm in eyes with acute DON and 73 ± 12 μm in control eyes (p = 0.014). In a multivariable analysis, patients with greater inferior peripapillary RNFL thickness and younger age tended to have better visual acuity at the last visit (p = 0.034, odds ratio [OR] = 1.038 and p = 0.007, OR = 0.912, respectively).
conclusionsOur data revealed a notable difference in temporal peripapillary RNFL thickness in eyes with chronic DON compared to eyes with acute DON and control eyes. We also found a significant association between inferior peripapillary RNFL thickness and visual acuity at the last visit. Thicker inferior peripapillary RNFL thickness was associated with better visual outcome. Further studies with large sample sizes using a prospective design should more clearly reveal the time aspect of the association between the onset of DON and the changes in peripapillary RNFL, and their clinical significance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.