SynthesisJournal of orthopaedic surgery and research2016
Minimally invasive plate osteosynthesis vs conventional fixation techniques for surgically treated humeral shaft fractures: a meta-analysis.
Synthesis in Journal of orthopaedic surgery and research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of humeral shaft fracture (OTA/AO 12) complicated with iatrogenic radial nerve injury.European journal of medical research · 2024Pooled it
- The radial nerve bridging plate technique for humeral shaft fractures: an approach facilitating plate removal without impeding fracture union - a case series.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Operative time, postoperative pain, and functional recovery in MIPO versus ORIF for humeral shaft fractures: a retrospective cohort case series.Annals of medicine and surgery (2012) · 2026Article
- Risk factors associated with delayed union after open reduction and plate fixation for humeral diaphyseal fractures.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Article
- A Bibliometric Analysis of the Top 50 Most Cited Articles on Iatrogenic Nerve Injuries of the Upper Limb Following Surgery.Journal of brachial plexus and peripheral nerve injury · 2025Review
- Complications and morbidity of the extended delto-pectoral approach in treating complex humeral shaft fractures with proximal metaphyseal extension using a long locking plate for internal fixation.BMC musculoskeletal disorders · 2024Article
- Comparison of Posterior and Anterolateral Surgical Approaches in Treating Adult Humeral Shaft Fractures.Cureus · 2023Article
- Compare the clinical value of two minimally invasive approaches to locating radial nerve in the posterior humeral approach.BMC musculoskeletal disorders · 2023Article
- HUMERAL SHAFT FRACTURE WITH AN INTACT WEDGE FRAGMENT: MIPO VS CONVENTIONAL PLATING.Acta ortopedica brasileira · 2023Article
- Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review.World journal of orthopedics · 2022Article
- Intramedullary Nailing Versus Plate Fixation for Humeral Shaft Fractures: A Systematic Review and Meta-Analysis.The archives of bone and joint surgery · 2022Review
- Comparison between osteosynthesis with interlocking nail and minimally invasive plating for proximal- and middle-thirds of humeral shaft fractures.International orthopaedics · 2021Article
- Is Minimally Invasive Plating Osteosynthesis Better Than Conventional Open Plating for Humeral Shaft Fractures? A Systematic Review and Meta-Analysis of Comparative Studies.Indian journal of orthopaedics · 2021Review
- Anterior minimally invasive plating osteosynthesis technique (MIPO) for humeral shaft fractures: an anatomical study of neuromuscular structures at risk.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Article
- Article
- Comparison of the Posterior and Anterolateral Surgical Approaches in the Treatment of Humeral Mid-Shaft Fractures: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Open reduction and internal fixation of humeral midshaft fractures: anterior versus posterior plate fixation.BMC musculoskeletal disorders · 2019Article
- Lateral Subcutaneous Locking Compression Plate and Small Incision Reduction for Distal-third Diaphyseal Humerus Fractures.Orthopaedic surgery · 2018Article
- Interventions for humeral shaft fractures: mixed treatment comparisons of clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Surgical interventions to treat humerus shaft fractures: A network meta-analysis of randomized controlled trials.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn this study, we performed a meta-analysis to identify whether minimally invasive plate osteosynthesis (MIPO) was superior to conventional fixation techniques (CFT) for treating humeral shaft fractures.
methodsA systematic literature search was conducted up to February 2016 in ScienceDirect, Springer, MEDLINE, and PubMed databases for relevant papers that compared the outcomes of MIPO with CFT, such as open reduction with plate osteosynthesis (ORPO) and intramedullary nail (IMN) for treating humeral shaft fractures. Meta-analysis was performed with Review Manager 5.0 software.
resultsAccording to the search strategy, eight studies that covered 391 patients were enrolled, including four randomized controlled trials (RCTs), two prospective cohort trials, and two retrospective cohort trials. Our meta-analysis did not detect any significant difference between MIPO and CFT (IMN and ORPO) in terms of operative time, fracture union rate, and fracture union time. However, MIPO has a less rate of complications and iatrogenic radial nerve palsy than that of ORPO and higher adjacent joint function scores than those of IMN (p < 0.05).
conclusionsBased on the present evidence, this meta-analysis suggested that MIPO was a better choice for treating humeral shaft fractures than CFT. However, more high-quality randomized trials are still needed to further confirm this conclusion in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.