Evidence map›Paper›PMID 27169570›Full record

ArticleNatural products and bioprospecting2016

Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides.

Caroline Alves Breda, Alessandra Marcon Gasperini, Vera Lucia Garcia, Karin Maia Monteiro, Giovana Anceski Bataglion, Marcos Nogueira Eberlin, Marta Cristina Teixeira Duarte

Abstract read
In one paragraph

Article in Natural products and bioprospecting, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Oxidative medicine and cellular longevity · 2020
    Article
  5. Piquiá Shells (Oxidative medicine and cellular longevity · 2020
    Article
  6. Article
  7. Neuroprotective Effect ofOxidative medicine and cellular longevity · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline Alves BredaSchool of Food Engineering, State University of Campinas, UNICAMP, Monteiro Lobato Street, 80, Barão Geraldo, Campinas, São Paulo, 13083-862, Brazil. carol_breda@yahoo.com.br.
Alessandra Marcon GasperiniSchool of Food Engineering, State University of Campinas, UNICAMP, Monteiro Lobato Street, 80, Barão Geraldo, Campinas, São Paulo, 13083-862, Brazil.
Vera Lucia GarciaOrganic Chemistry and Pharmaceutical Division of Research Center for Chemistry, Biology and Agriculture - CPQBA, University of Campinas, UNICAMP, Alexandre Cazelatto Street, 999, Betel, Paulínia, São Paulo, 13148-218, Brazil.
Karin Maia MonteiroPharmacology and Toxicology Division of Research Center for Chemistry, Biology and Agriculture - CPQBA, University of Campinas, UNICAMP, Alexandre Cazelatto Street, 999, Betel, Paulínia, São Paulo, 13148-218, Brazil.
Giovana Anceski BataglionThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas, UNICAMP, Campinas, São Paulo, 13084-971, Brazil.
Marcos Nogueira EberlinThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas, UNICAMP, Campinas, São Paulo, 13084-971, Brazil.
Marta Cristina Teixeira DuarteMicrobiology Division of Research Center for Chemistry, Biology and Agriculture - CPQBA, University of Campinas, UNICAMP, Alexandre Cazelatto Street, 999, Betel, Paulínia, São Paulo, 13148-218, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing demand for safe food without preservatives or pesticides residues has encouraged several studies on natural products with antifungal activity and low toxicity. In this study, ethanolic extracts from leaves and fruit residues (peel and seeds) of three Brazilian savanna species (Acrocomia aculeata, Campomanesia adamantium and Caryocar brasiliense) were evaluated against phytopathogenic fungi. Additionally, the most active extract was chemically characterized by ESI-MS and its oral acute toxicity was evaluated. Extracts from C. brasiliense (pequi) peel and leaves were active against Alternaria alternata, Alternaria solani and Venturia pirina with minimal inhibitory concentrations between 350 and 1000 µg/mL. When incorporated in solid media, these extracts extended the lag phase of A. alternata and A. solani and reduced the growth rate of A. solani. Pequi peel extract showed better antifungal activity and their ESI-MS analysis revealed the presence of substances widely reported as antifungal such as gallic acid, quinic acid, ellagic acid, glucogalin and corilagin. The oral acute toxicity was relatively low, being considered safe for use as a potential natural fungicide.

Indexed as

Brazilian savanna fruitsNatural fungicidesPhytopathogensResidues

Identifiers

PMID27169570
PMCPMC4940252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.