ArticleBMC oral health2016
Cariogenicity features of Streptococcus mutans in presence of rubusoside.
Article in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Effect of rubusoside, a natural sucrose substitute, on the metabolism of Scardovia wiggsiae: a novel potential cariogenic pathogen.BMC biology · 2025Article
- The Antimicrobial Effect of a Low-Frequency Square Wave Compared to Chlorhexidine.Journal of clinical medicine · 2025Article
- The impact ofFrontiers in dental medicine · 2025Article
- Antibacterial and Antiviral Properties ofFoods (Basel, Switzerland) · 2023Article
- Impact of Dairy Products and Plant-Based Alternatives on Dental Health: Food Matrix Effects.Nutrients · 2023Review
- Age- and Microbiota-Dependent Cell Stemness Plasticity Revealed by Cattle Cell Landscape.Research (Washington, D.C.) · 2023Article
- Microbiota-host crosstalk in the newborn and adult rumen at single-cell resolution.BMC biology · 2022Article
- Comparative Metabolomics Analysis of Stigmas and Petals in Chinese Saffron (Plants (Basel, Switzerland) · 2022Article
- Article
- Anti-Bacterial Properties of Cannabigerol TowardFrontiers in microbiology · 2021Article
- Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation.Molecules (Basel, Switzerland) · 2020Review
- Effect of Rubusoside, a Natural Sucrose Substitute, on Streptococcus mutans Biofilm Cariogenic Potential and Virulence Gene ExpressionApplied and environmental microbiology · 2020Article
- Antimicrobial Effect of a Peptide Containing Novel Oral Spray onBioMed research international · 2020Article
- Anti-cariogenic Characteristics of Rubusoside.Biotechnology and bioprocess engineering : BBE · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne promising way of reducing caries is by using sucrose substitutes in food. rubusoside is a prototype sweet substance isolated from the leaves of the plant Rubrus suavissimus S. Lee. (Rosaceae), and is rated sweeter than sucrose. The purpose of this study was to investigate the effects of rubusoside on Streptococcus mutans growth, acidogenicity, and adherence to glass in vitro.
methodsThe effects of rubusoside on the growth and glass surface adhering of Streptococcus mutans were investigated by measuring the optical density of the culture at 540 nm with a spectrophotometer. Rubusoside influence on Streptococcus mutans acidogenicity was determined by measuring the pH of the culture. Sucrose, glucose, maltose, fructose and xylitol were designed to compare with rubusoside.
resultsS. mutans growth in the rubusoside-treated group was significantly lower than that in the sucrose, glucose, maltose and fructose groups (p < 0.05) except for xylitol group (p > 0.05). Sucrose-treated S. mutans exhibited the highest adherence to glass, and rubusoside-treated S. mutans exhibited the lowest. S. mutans adherence to a glass surface and acidogenicity with sucrose were significantly reduced by rubusoside.
conclusionsRubusoside may have some potential as a non-cariogenic, non-caloric sweetener.
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