ArticleInfectious diseases of poverty2016
Diagnostic evaluation of rapid tests for scrub typhus in the Indian population is needed.
Article in Infectious diseases of poverty, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Review
- Article
- Development and implementation of a strategy for early diagnosis and management of scrub typhus: an emerging public health threat.Frontiers in public health · 2024Article
- Review
- Cutaneous Manifestations and Neurological Diseases.Cureus · 2023Review
- Screening and genotyping of Orientia tsutsugamushi from field-collected on-host chiggers (Acari: Prostigmata) recovered from a positive scrub typhus locality in Kelantan, Malaysia.Experimental & applied acarology · 2021Article
- Validation of a Clinical Risk-scoring Algorithm for Scrub Typhus Severity in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Article
- Diagnosis of scrub typhus: recent advancements and challenges.3 Biotech · 2020Review
- Clinical and Epidemiological Patterns of Scrub Typhus, an Emerging Disease in Bhutan.Tropical medicine and infectious disease · 2019Article
- A review of the global epidemiology of scrub typhus.PLoS neglected tropical diseases · 2017Review
- Clinical and paraclinical profile, and predictors of outcome in 90 cases of scrub typhus, Meghalaya, India.Infectious diseases of poverty · 2016Article
- State of the Globe: What's the Right Test for Diagnosing Rickettseal Diseases.Journal of global infectious diseasesArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOwing to frequent outbreaks witnessed in different parts of the country in the recent past, scrub typhus is being described as a re-emerging infectious disease in India. Differentiating scrub typhus from other endemic diseases like malaria, leptospirosis, dengue fever, typhoid, etc. is difficult due to overlapping clinical features and a lower positivity for eschars in Asian populations. Hence, the diagnosis heavily relies on laboratory tests. DISCUSSION: Costs and the need of technical expertise limit the wide use of indirect immunoperoxidase or immunofluorescence assays, ELISA and PCR. The Weil-Felix test is the most commonly used and least expensive serological test, but lacks both sensitivity and specificity. Hence, the diagnosis of scrub typhus is often delayed or overlooked. With due consideration of the cost, rapidity, single test result and simplicity of interpretation, rapid diagnostic tests have come into vogue. However, evaluation of rapid diagnostic tests for scrub typhus in the Indian population is needed to justify or discourage their use.
conclusionResearch studies are needed to find the most suitable test in terms of the rapidity of the result, simplicity of the procedure, ease of interpretation and cost to be used in the Indian populace.
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