ArticleBMC genomics2016
Genome-wide identification and functional prediction of nitrogen-responsive intergenic and intronic long non-coding RNAs in maize (Zea mays L.).
Article in BMC genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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67 citing papers in PubMed, 132 citations in OpenAlex.
- Non-coding RNAs as central regulators of phytohormone signaling in plant abiotic stress responses.Plant molecular biology · 2026Review
- Integrative Analysis of lncRNA-RBP (RNA-Binding Protein) Regulatory Networks Reveals Molecular Targets for EnhancingInternational journal of molecular sciences · 2026Article
- The lncRNA LOC100257036 and vvimiR156 modulate gibberellin signaling through AGAMOUS during cluster formation in Sistan Yaghooti grape.Scientific reports · 2025Article
- Transcriptomic analysis reveals role of lncRNA LOC100257036 to regulate AGAMOUS during cluster compactness of Vitis vinifera cv. sistan yaghooti.Scientific reports · 2024Article
- MicroRNAs as potent regulators in nitrogen and phosphorus signaling transduction and their applications.Stress biology · 2024Review
- Underground communication: Long non-coding RNA signaling in the plant rhizosphere.Plant communications · 2024Review
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- Characterization of arbuscular mycorrhizal fungal species associating withFrontiers in plant science · 2024Article
- Long noncoding RNA from Betula platyphylla, BplncSIR1, confers salt tolerance by regulating BpNAC2 to mediate reactive oxygen species scavenging and stomatal movement.Plant biotechnology journal · 2024Article
- Insights into the roles of long noncoding RNAs in the communication between plants and the environment.The plant genome · 2023Review
- The expression landscape and pangenome of long non-coding RNA in the fungal wheat pathogenMicrobial genomics · 2023Article
- Progress of Research on the Physiology and Molecular Regulation of Sorghum Growth under Salt Stress by Gibberellin.International journal of molecular sciences · 2023Review
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- Regulation of seed oil accumulation by lncRNAs in Brassica napus.Biotechnology for biofuels and bioproducts · 2023Article
- Genome-wide identification of long non-coding RNAs and their potential functions in radish response to salt stress.Frontiers in genetics · 2023Article
- Genome-wide analysis of long non-coding RNAs (lncRNAs) in tea plants (Frontiers in plant science · 2023Article
- Global Identification of White Lupin lncRNAs Reveals Their Role in Cluster Roots under Phosphorus Deficiency.International journal of molecular sciences · 2022Article
- Identification and characterization of heat-responsive lncRNAs in maize inbred line CM1.BMC genomics · 2022Article
- Whole-transcriptome analysis and construction of an anther development-related ceRNA network in Chinese cabbage (Brassica campestris L. ssp. pekinensis).Scientific reports · 2022Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNitrogen (N) is an essential and often limiting nutrient to plant growth and development. Previous studies have shown that the mRNA expressions of numerous genes are regulated by nitrogen supplies; however, little is known about the expressed non-coding elements, for example long non-coding RNAs (lncRNAs) that control the response of maize (Zea mays L.) to nitrogen. LncRNAs are a class of non-coding RNAs larger than 200 bp, which have emerged as key regulators in gene expression.
resultsIn this study, we surveyed the intergenic/intronic lncRNAs in maize B73 leaves at the V7 stage under conditions of N-deficiency and N-sufficiency using ribosomal RNA depletion and ultra-deep total RNA sequencing approaches. By integration with mRNA expression profiles and physiological evaluations, 7245 lncRNAs and 637 nitrogen-responsive lncRNAs were identified that exhibited unique expression patterns. Co-expression network analysis showed that the nitrogen-responsive lncRNAs were enriched mainly in one of the three co-expressed modules. The genes in the enriched module are mainly involved in NADH dehydrogenase activity, oxidative phosphorylation and the nitrogen compounds metabolic process.
conclusionsWe identified a large number of lncRNAs in maize and illustrated their potential regulatory roles in response to N stress. The results lay the foundation for further in-depth understanding of the molecular mechanisms of lncRNAs' role in response to nitrogen stresses.
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