Evidence map›Paper›PMID 27168850›Full record

ArticleExperimental and therapeutic medicine2016

Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-κB signaling pathways.

Lixia Lou, Jingwei Zhou, Yujun Liu, Y I Wei, Jiuli Zhao, Jiagang Deng, Bin Dong, Lingqun Zhu, Aiming Wu, Yingxi Yang and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
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  11. Ethanol extract ofExperimental and therapeutic medicine · 2023
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  12. Review
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  15. Review
  16. Review
  17. Can chlorogenic acid reduce oxidative stress and in an experimental spinal cord injury?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  18. The Herbal Combination ofFrontiers in pharmacology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Lixia LouKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Jingwei ZhouDepartment of Renal Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Yujun LiuDepartment of Rheumatology, Putuo District Center Hospital, Shanghai 200000, P.R. China.
Y I WeiKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Jiuli ZhaoKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Jiagang DengSchool of Pharmacy, Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, P.R. China.
Bin DongKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Lingqun ZhuKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Aiming WuKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Yingxi YangKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Limin ChaiKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R. China.
Beijing University of Chinese Medicine · CNCentral Hospital of Putuo District · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNGuangxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorogenic acid (CGA) is the primary constituent of Caulis

Indexed as

apoptosischlorogenic acidfibroblast-like synoviocytesinterleukin-6Janus-activated kinase/signal transducer and activator of transcription 3nuclear factor-κB

Identifiers

PMID27168850
PMCPMC4840502
OpenAlexW2296287575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.