ArticleExperimental and therapeutic medicine2016
Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease.
Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patient-reported outcomes in autosomal inherited bleeding disorders: A systematic literature review.Haemophilia : the official journal of the World Federation of Hemophilia · 2022Pooled it
- Recombinant von Willebrand factor and tranexamic acid for heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA (VWDMin): a phase 3, open-label, randomised, crossover trial.The Lancet. Haematology · 2023Trial
- Seventh Åland Island Meeting on von Willebrand Disease.Haemophilia : the official journal of the World Federation of Hemophilia · 2026Article
- Dealing with heavy menstrual bleeding in very rare bleeding disorders: from a patient's perspective.Research and practice in thrombosis and haemostasis · 2026Article
- Beyond a century of discovery: the global and persistent burden of underdiagnosis in von Willebrand disease.Research and practice in thrombosis and haemostasis · 2026Review
- Gynecologic and obstetric management of girls and women with von Willebrand disease.Haematologica · 2026Review
- Health-related quality of life in adults with von Willebrand disease: results of the French real-life Willebrand study on health-related quality of life.Research and practice in thrombosis and haemostasis · 2026Article
- Von Willebrand disease: more than just a bleeding disorder.Research and practice in thrombosis and haemostasis · 2026Review
- Outcomes and Healthcare Resource Utilisation in Adults With von Willebrand Disease Treated With Recombinant von Willebrand Factor in Surgical Settings in the United Kingdom.European journal of haematology · 2026Article
- Outcomes and Healthcare Resource Utilisation in Adults With von Willebrand Disease Receiving On-Demand Recombinant von Willebrand Factor in the United Kingdom.European journal of haematology · 2026Article
- Prevalence and Impact of Heavy Menstrual Bleeding in Women With von Willebrand Disease Across Age Groups: A Retrospective Study.Haemophilia : the official journal of the World Federation of Hemophilia · 2025Article
- Article
- How should abnormal uterine bleeding be managed in people with bleeding disorders: a systematic review of the literature and thematic synthesis.Research and practice in thrombosis and haemostasis · 2025Review
- Prevalence of heavy menstrual bleeding, iron deficiency, iron deficiency anemia, and treatment in women with von Willebrand disease-a cohort study.Research and practice in thrombosis and haemostasis · 2025Article
- Sexuality and bleeding in von Willebrand disease.Research and practice in thrombosis and haemostasis · 2025Article
- Adherence and Quality of Life in Adult Patients With Haemophilia A, Haemophilia B and Von Willebrand Disease: A National Cross-Sectional Survey.European journal of haematology · 2025Article
- Prophylaxis in von Willebrand disease with von Willebrand factor concentrate and nonfactor therapies.Research and practice in thrombosis and haemostasis · 2024Article
- von Willebrand factor/factor VIII concentrate (Wilate) prophylaxis in children and adults with von Willebrand disease.Blood advances · 2024Article
- Tranexamic acid for management of heavy vaginal bleeding: barriers to access and myths surrounding its use.Research and practice in thrombosis and haemostasis · 2024Article
- Von Willebrand Disease Epidemiology, Burden of Illness and Management: A Systematic Review.Journal of blood medicine · 2023Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Women with the inherited bleeding disorder von Willebrand's disease (VWD) face gender-specific hemostatic challenges during menstruation. Heavy menstrual bleeding (HMB) can negatively affect their overall life activities and the health-associated quality of life. The purpose of the present study was to investigate whether women with VWD experienced HMB and an impaired health-associated quality of life. The study subjects were recruited from the Coagulation Unit of Karolinska University Hospital. Information was retrieved from various self-administered forms and medical records. Of the 30 women (18-52 years) that were included in the present study, 50% suffered from HMB, although the majority received treatment for HMB. In addition, almost all the included women perceived limitations in the overall life activities due to menstruation. The health-associated quality of life for women with HMB was significantly lower (P<0.10) with regards to 'bodily pain' compared with Swedish women of the general population. In conclusion, women with VWD experienced reduced health-associated quality of life as a result of HMB. Therefore, preventing limitations in overall life activities and improving their health-associated quality of life thorough counseling on menstrual bleeding is important for women with VWD.
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