Evidence map›Paper›PMID 27168722›Full record

ReviewBioinformatics and biology insights2016

Practical Approaches for Mining Frequent Patterns in Molecular Datasets.

Stefan Naulaerts, Sandy Moens, Kristof Engelen, Wim Vanden Berghe, Bart Goethals, Kris Laukens, Pieter Meysman

Abstract readReview
In one paragraph

Review in Bioinformatics and biology insights, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefan NaulaertsDepartment of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.; Biomedical Informatics Research Center Antwerpen (Biomina), University of Antwerp/Antwerp University Hospital, Antwerp, Belgium.
Sandy MoensDepartment of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.
Kristof EngelenDepartment of Computational Biology, Fondazione Edmund Mach, San Michele all'Adige, Trento, Italy.
Wim Vanden BergheDepartment of Biomedical Sciences, Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES), University of Antwerp, Antwerp, Belgium.
Bart GoethalsDepartment of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.
Kris LaukensDepartment of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.; Biomedical Informatics Research Center Antwerpen (Biomina), University of Antwerp/Antwerp University Hospital, Antwerp, Belgium.
Pieter MeysmanDepartment of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.; Biomedical Informatics Research Center Antwerpen (Biomina), University of Antwerp/Antwerp University Hospital, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pattern detection is an inherent task in the analysis and interpretation of complex and continuously accumulating biological data. Numerous itemset mining algorithms have been developed in the last decade to efficiently detect specific pattern classes in data. Although many of these have proven their value for addressing bioinformatics problems, several factors still slow down promising algorithms from gaining popularity in the life science community. Many of these issues stem from the low user-friendliness of these tools and the complexity of their output, which is often large, static, and consequently hard to interpret. Here, we apply three software implementations on common bioinformatics problems and illustrate some of the advantages and disadvantages of each, as well as inherent pitfalls of biological data mining. Frequent itemset mining exists in many different flavors, and users should decide their software choice based on their research question, programming proficiency, and added value of extra features.

Indexed as

frequent itemset mininggene expressionMycobacterium tuberculosisprotein domain structureprotein–protein interaction

Identifiers

PMID27168722
PMCPMC4856181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.