Evidence map›Paper›PMID 27168663›Full record

ArticlePublic health reports (Washington, D.C. : 1974)

Efforts at the Frontlines: Implementing a Hepatitis C Testing and Linkage-to-Care Program at the Local Public Health Level.

Arlene C Seña, Sarah J Willis, Alison Hilton, Alexandria Anderson, David A Wohl, Christopher B Hurt, Andrew J Muir

Open access · bronzeAbstract read
In one paragraph

Article in Public health reports (Washington, D.C. : 1974). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Potential Impact of Frequent Testing for Hepatitis C Virus Among People Who Inject Drugs Toward Hepatitis C Elimination in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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  8. Review
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  15. Hepatitis C Screening: Barriers to Linkage to Care.Journal of clinical and translational hepatology · 2019
    Article
  16. Article
  17. Review
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  19. Article
  20. Building a Hepatitis C Clinical Program: Strategies to Optimize Outcomes.Current treatment options in infectious diseases · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Arlene C SeñaDurham County Department of Public Health, Durham, NC; University of North Carolina at Chapel Hill, Department of Medicine, Institute for Global Health and Infectious Diseases, Chapel Hill, NC.
Sarah J WillisUniversity of North Carolina, Gillings School of Global Public Health, Department of Epidemiology, Chapel Hill, NC.
Alison HiltonDurham County Department of Public Health, Durham, NC.
Alexandria AndersonDurham County Department of Public Health, Durham, NC.
David A WohlUniversity of North Carolina at Chapel Hill, Department of Medicine, Institute for Global Health and Infectious Diseases, Chapel Hill, NC.
Christopher B HurtUniversity of North Carolina at Chapel Hill, Department of Medicine, Institute for Global Health and Infectious Diseases, Chapel Hill, NC.
Andrew J MuirDuke University School of Medicine, Division of Gastroenterology and Duke Clinical Research Institute, Durham NC.
University of North Carolina at Chapel Hill · USDurham County Department of Public Health · USDuke University · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

objectivesThe national Viral Hepatitis Action Plan recommends strengthening partnerships among health departments, community-based organizations, and health-care providers for hepatitis services. We implemented a hepatitis C virus (HCV) testing and linkage-to-care program through a local health department using similar strategies reported for HIV care.

methodsThe Durham County Department of Public Health received federal funding to conduct HCV testing and linkage to care in Durham, North Carolina. HCV antibody testing with reflex RNA was offered through a sexually transmitted disease clinic, a county jail, community testing sites (including a residential substance abuse recovery program), and a homeless clinic. People with evidence of HCV infection were linked to care through an HCV bridge counselor who provided education, incentives, and transportation, and scheduled appointments with HCV specialists at nearby academic centers and on-site clinics.

resultsFrom December 2012 through February 2014, we conducted 2,004 HCV tests, of which 326 (16.3%) were HCV antibody positive and 241 (12.0%) had detectable HCV RNA. Among the 241 people with HCV infection, 178 (73.9%) were men, and 133 (55.2%) were born between 1945 and 1965. Of 241 people with chronic HCV infection, 150 (62.2%) reported ever injecting drugs, eight (2.5%) were coinfected with HIV, and 123 (51.0%) were linked to care.

conclusionAt the local public health level, HCV testing and linkage to care can be facilitated with additional funding and by leveraging existing programs and provider networks to deliver a coordinated system of care.

Indexed as

Public Health AdministrationAdultCooperative BehaviorFemaleHealth PromotionHealth Services AccessibilityHepacivirusHepatitis CHepatitis C AntibodiesHumansMaleMiddle AgedNorth CarolinaPrevalencePrisonsHepatitis C Antibodies

Identifiers

PMID27168663
PMCPMC4853330
OpenAlexW2409500331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.