Evidence map›Paper›PMID 27168187›Full record

SynthesisPloS one2016

Quality of Reporting and Study Design of CKD Cohort Studies Assessing Mortality in the Elderly Before and After STROBE: A Systematic Review.

Anirudh Rao, Katharina Brück, Shona Methven, Rebecca Evans, Vianda S Stel, Kitty J Jager, Lotty Hooft, Yoav Ben-Shlomo, Fergus Caskey

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Anirudh RaoUK Renal Registry, Bristol, United Kingdom.ORCID 0000-0002-3202-2832
Katharina BrückERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center - University of Amsterdam, Amsterdam, The Netherlands.
Shona MethvenUK Renal Registry, Bristol, United Kingdom.
Rebecca EvansUK Renal Registry, Bristol, United Kingdom.
Vianda S StelERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center - University of Amsterdam, Amsterdam, The Netherlands.
Kitty J JagerERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center - University of Amsterdam, Amsterdam, The Netherlands.
Lotty HooftDutch Cochrane Centre, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Yoav Ben-ShlomoUK Renal Registry, Bristol, United Kingdom.
Fergus CaskeyUK Renal Registry, Bristol, United Kingdom.
Renal Association · GBAmsterdam UMC Location University of Amsterdam · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement was published in October 2007 to improve quality of reporting of observational studies. The aim of this review was to assess the impact of the STROBE statement on observational study reporting and study design quality in the nephrology literature. STUDY

designSystematic literature review. SETTING & POPULATION: European and North American, Pre-dialysis Chronic Kidney Disease (CKD) cohort studies. SELECTION CRITERIA FOR STUDIES: Studies assessing the association between CKD and mortality in the elderly (>65 years) published from 1st January 2002 to 31st December 2013 were included, following systematic searching of MEDLINE & EMBASE. PREDICTOR: Time period before and after the publication of the STROBE statement. OUTCOME: Quality of study reporting using the STROBE statement and quality of study design using the Newcastle Ottawa Scale (NOS), Scottish Intercollegiate Guidelines Network (SIGN) and Critical Appraisal Skills Programme (CASP) tools.

results37 papers (11 Pre & 26 Post STROBE) were identified from 3621 potential articles. Only four of the 22 STROBE items and their sub-criteria (objectives reporting, choice of quantitative groups and description of and carrying out sensitivity analysis) showed improvements, with the majority of items showing little change between the period before and after publication of the STROBE statement. Pre- and post-period analysis revealed a Manuscript STROBE score increase (median score 77.8% (Inter-quartile range [IQR], 64.7-82.0) vs 83% (IQR, 78.4-84.9, p = 0.05). There was no change in quality of study design with identical median scores in the two periods for NOS (Manuscript NOS score 88.9), SIGN (Manuscript SIGN score 83.3) and CASP (Manuscript CASP score 91.7) tools. LIMITATIONS: Only 37 Studies from Europe and North America were included from one medical specialty. Assessment of study design largely reliant on good reporting.

conclusionsThis study highlights continuing deficiencies in the reporting of STROBE items and their sub-criteria in cohort studies in nephrology. There was weak evidence of improvement in the overall reporting quality, with no improvement in methodological quality of CKD cohort studies between the period before and after publication of the STROBE statement.

Indexed as

Observational Studies as TopicResearch DesignResearch ReportAgedCohort StudiesHumansLinear ModelsObserver VariationRenal Insufficiency, Chronic

Identifiers

PMID27168187
PMCPMC4863970
OpenAlexW2348056899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.