ArticleHeadache2016
Adherence to Biobehavioral Recommendations in Pediatric Migraine as Measured by Electronic Monitoring: The Adherence in Migraine (AIM) Study.
Article in Headache, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Engagement and predictors of use of a smartphone app for migraine self-management: A secondary analysis of the EMMA trial.Headache · 2026Trial
- Multimodal Assessment of Medication Adherence Among Youth With Migraine: An Ancillary Study of the CHAMP Trial.Journal of pediatric psychology · 2022Trial
- Treatment Adherence in Child and Adolescent Chronic Migraine Patients: Results From the Cognitive-Behavioral Therapy and Amitriptyline Trial.The Clinical journal of pain · 2017Trial
- Characterizing migraine burden and treatment response using nationwide smartphone app-based data in Korea.The journal of headache and pain · 2026Article
- Hydration and primary headaches in children and adolescents: a prospective interventional study.BMJ nutrition, prevention & health · 2026Article
- Protocol for a randomized controlled trial evaluating a digital behavioral self-management intervention for adolescent migraine.Applied nursing research : ANR · 2025Article
- Pediatric medication management barriers faced by providers serving underserved populations and proposed solutions.Frontiers in health services · 2025Article
- Remote electrical neuromodulation (REN) wearable device for adolescents with migraine: a real-world study of high-frequency abortive treatment suggests preventive effects.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Burden of disease and lifestyle habits in adolescents and young adults prone to frequent episodic migraine: A secondary comparative analysis.Journal of child health care : for professionals working with children in the hospital and community · 2022Article
- Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review.JMIR mHealth and uHealth · 2022Review
- Management of Chronic Migraine in Children and Adolescents: Where are We in 2022?Pediatric health, medicine and therapeutics · 2022Review
- Towards eHealth to support the health journey of headache patients: a scoping review.Journal of neurology · 2021Article
- Headache in Children and Adolescents.Continuum (Minneapolis, Minn.) · 2021Review
- Telemedicine in Pediatric Headache: A Review and Practical Implementation.Current neurology and neuroscience reports · 2021Review
- Efficacy and Feasibility of Behavioral Treatments for Migraine, Headache, and Pain in the Acute Care Setting.Current pain and headache reports · 2020Review
- Lifestyle Modifications to Help Prevent Headache at a Developmental Age.Frontiers in neurology · 2020Review
- Prophylactic Treatment of Pediatric Migraine: Is There Anything New in the Last Decade?Frontiers in neurology · 2019Review
- Availability of researcher-led eHealth tools for pain assessment and management: barriers, facilitators, costs, and design.Pain reports · 2018Article
- Digital Technology and Mobile Health in Behavioral Migraine Therapy: a Narrative Review.Current pain and headache reports · 2018Review
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
objectiveThe purpose of this investigation was to examine treatment adherence to medication and lifestyle recommendations among pediatric migraine patients using electronic monitoring systems.
backgroundNonadherence to medical treatment is a significant public health concern, and can result in poorer treatment outcomes, decreased cost-effectiveness of medical care, and increased morbidity. No studies have systematically examined adherence to medication and lifestyle recommendations in adolescents with migraine outside of a clinical trial.
methodsParticipants included 56 adolescents ages 11-17 who were presenting for clinical care. All were diagnosed with migraine with or without aura or chronic migraine and had at least 4 headache days per month. Medication adherence was objectively measured using electronic monitoring systems (Medication Event Monitoring Systems technology) and daily, prospective self-report via personal electronic devices. Adherence to lifestyle recommendations of regular exercise, eating, and fluid intake were also assessed using daily self-report on personal electronic devices.
resultsElectronic monitoring indicates that adolescents adhere to their medication 75% of the time, which was significantly higher than self-reported rates of medication adherence (64%). Use of electronic monitoring of medication detected rates of adherence that were significantly higher for participants taking once daily medication (85%) versus participants taking twice daily medication (59%). Average reported adherence to lifestyle recommendations of consistent noncaffeinated fluid intake (M = 5 cups per day) was below recommended levels of a minimum of 8 cups per day. Participants on average also reported skipping 1 meal per week despite recommendations of consistently eating three meals per day.
conclusionsResults suggest that intervention focused on adherence to preventive treatments (such as medication) and lifestyle recommendations may provide more optimal outcomes for children and adolescents with migraine and their families. Once daily dosing of medication may be preferred to twice daily medication for increased medication adherence among children and adolescents.
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Registered trials
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