Evidence map›Paper›PMID 27167437›Full record

ReviewJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2016

New anticoagulants for the treatment of venous thromboembolism.

Caio Julio Cesar Dos Santos Fernandes, José Leonidas Alves Júnior, Francisca Gavilanes, Luis Felipe Prada, Luciana Kato Morinaga, Rogerio Souza

Open access · diamondAbstract readReview
In one paragraph

Review in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Brazilian guidelines for the pharmacological treatment of pulmonary embolism. Official document of the Brazilian Thoracic Association based on the GRADE methodology.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Challenges in the management of patients with pulmonary embolism in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  7. Brazilian Thoracic Society recommendations for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cancer-associated thrombosis: the when, how and why.European respiratory review : an official journal of the European Respiratory Society · 2019
    Review
  13. Reperfusion in acute pulmonary thromboembolism.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2018
    Article
  14. Article
  15. Momentum.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
  16. Evolution in the management of non-small cell lung cancer in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
  17. Review
  18. The need for a balance between highly prevalent diseases and neglected diseases.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
  19. Vascular reperfusion in pulmonary thromboembolism: certainties and uncertainties.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Caio Julio Cesar Dos Santos FernandesFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
José Leonidas Alves JúniorFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Francisca GavilanesFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Luis Felipe PradaFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Luciana Kato MorinagaFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Rogerio SouzaFaculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstituto do Coração · PTUniversidade Brasil · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, venous thromboembolism (VTE) is among the leading causes of death from cardiovascular disease, surpassed only by acute myocardial infarction and stroke. The spectrum of VTE presentations ranges, by degree of severity, from deep vein thrombosis to acute pulmonary thromboembolism. Treatment is based on full anticoagulation of the patients. For many decades, it has been known that anticoagulation directly affects the mortality associated with VTE. Until the beginning of this century, anticoagulant therapy was based on the use of unfractionated or low-molecular-weight heparin and vitamin K antagonists, warfarin in particular. Over the past decades, new classes of anticoagulants have been developed, such as factor Xa inhibitors and direct thrombin inhibitors, which significantly changed the therapeutic arsenal against VTE, due to their efficacy and safety when compared with the conventional treatment. The focus of this review was on evaluating the role of these new anticoagulants in this clinical context.

Indexed as

AnticoagulantsDabigatranHumansPyrazolesPyridinesPyridonesRivaroxabanThiazolesTime FactorsVenous ThromboembolismWarfarinAnticoagulantsapixabanDabigatranedoxabanPyrazolesPyridinesPyridonesRivaroxabanThiazolesWarfarin

Identifiers

PMID27167437
PMCPMC4853069
OpenAlexW2345746005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.