ReviewAdvances in experimental medicine and biology2016
Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population.
Review in Advances in experimental medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Collection of human bacteria at University of Tartu, Estonia.Microbiology resource announcements · 2026Article
- Culture-based studies of intestinal lactobacilli in young people and centenarians.Frontiers in microbiology · 2026Article
- Beyond antibiotics: the expanding horizon of microbial natural products.Frontiers in antibiotics · 2026Review
- Comparing lactic acid bacteria biodiversity in irritable bowel syndrome and healthy gut microbiota.Food science & nutrition · 2024Article
- Impact of Limosilactobacillus fermentum probiotic treatment on gut microbiota composition in sahiwal calves with rotavirus diarrhea: A 16S metagenomic analysis study".BMC microbiology · 2024Article
- Comparative Analysis of Gut Microbiota in Centenarians and Young People: Impact of Eating Habits and Childhood Living Environment.Frontiers in cellular and infection microbiology · 2022Article
- The rising dominance of microbiology: what to expect in the next 15 years?Microbial biotechnology · 2022Article
- Novel investigations in retinoic-acid-induced cleft palate about the gut microbiome of pregnant mice.Frontiers in cellular and infection microbiology · 2022Article
- A Method of Direct Quantitation of Lactobacillus spp. in Intestinal Contents Based on Real-Time PCR.Bulletin of experimental biology and medicine · 2021Article
- Bacterial Natural Compounds with Anti-Inflammatory and Immunomodulatory Properties (Mini Review).Drug design, development and therapy · 2020Review
- Suboptimal community growth mediated through metabolite crossfeeding promotes species diversity in the gut microbiota.PLoS computational biology · 2018Article
- Adaptation and Probiotic Potential of Lactobacilli, Isolated from the Oral Cavity and Intestines of Healthy People.Probiotics and antimicrobial proteins · 2018Article
- Immunity to α-Gal: The Opportunity for Malaria and Tuberculosis Control.Frontiers in immunology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The complex ecosystem of the gastrointestinal tract involves tight interrelations among host cells, diet, and billions of microbes, both beneficial and opportunistic pathogens. In spite of advanced genomic, metagenomic, and metabonomic approaches, knowledge is still quite limited regarding the biodiversity of beneficial microbiota, including Lactobacillus spp., and its impact on the main biomarkers of general health. In this paper, Lactobacillus biodiversity is demonstrated through its taxonomy, function, and host-microbial interactions. Its prevalence, composition, abundance, intertwined metabolic properties, and relation to host age, genotype, and socioeconomic factors are reviewed based on the literature and original research experience. The species richness, e.g., the biodiversity of gut microbiota, provides the host with a variety of metabolically active species and strains that predict their response for different health conditions and extrinsic interventions. Metabolically active and safe Lactobacillus species and specific strains with particular functional properties increase the biodiversity of the whole intestinal microbiota. The elaborated principles for effective application of probiotics are discussed, aimed at regulating the composition of microbiota simultaneously with blood and urine biomarkers at the borderline of normality. This approach targets the impact of probiotic strains to maintenance of health with anti-infectious, cardiovascular, and metabolic support.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.