ArticleOncotarget2016
Effects of aging on the effectiveness of smoking cessation medication.
Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Socioeconomic inequalities and smoking cessation among Hungarian adults: evidence from the European health interview survey.Frontiers in public health · 2026Article
- Comparisons of factors correlated with successful smoking cessation between middle-aged and older smokers.PloS one · 2026Article
- Article
- "Smoking during pregnancy - Perinatal outcomes, financial implications, and tobacco treatment services".Preventive medicine reports · 2023Article
- Smoking Cessation Success and Affecting Factors in Geriatric Patients.Iranian journal of public health · 2023Article
- Psychosocial determinants of quit motivation in older smokers from deprived backgrounds: a cross-sectional survey.BMJ open · 2021Article
- Article
- Smoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Article
- Factors Correlated with Smoking Cessation Success in Older Adults: A Retrospective Cohort Study in Taiwan.International journal of environmental research and public health · 2019Article
- Comparative Effectiveness of Varenicline and Nicotine Replacement Therapy for Smoking Cessation in Older and Younger Smokers: A Prospective Cohort in Taiwan.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Cost-effectiveness of increasing the reach of smoking cessation interventions in Germany: results from the EQUIPTMOD.Addiction (Abingdon, England) · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConsidering the pharmacokinetic and pharmacodynamic aspects of different medications, it is plausible that the age of a smoker could affect the half-life of these drugs. The aim of this study was to compare the effectiveness of smoking cessation drugs (nicotine replacement therapy, bupropion, and varenicline) used either in isolation or in combination in adults under and over 60 years of age.
methodsData were collected from 940 Brazilian patients participating in a smoking cessation program. Participants were prescribed smoking cessation medication to be used for at least 12 weeks and were followed for 52 weeks.
resultsCessation rates were significantly different among younger and older participants who were using nicotine replacement therapy (NRT) alone. Being over 60 years of age was significantly associated with increased cessation success among those who used NRT alone (OR 2.34, 95% CI: 1.36 to 4.04, p = 0.002). The effectiveness of varenicline and bupropion were not significantly different according to age groups.
conclusionUsing age as a predictor for tailoring smoking cessation drugs might potentially lead to a more individualized prescription of smoking cessation therapy. These results should be tested in randomized controlled trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.