Evidence map›Paper›PMID 27166218›Full record

SynthesisJournal of the American Heart Association2016

False Lumen Status in Patients With Acute Aortic Dissection: A Systematic Review and Meta-Analysis.

Dongze Li, Lei Ye, Yarong He, Xiaoping Cao, Jining Liu, Wu Zhong, Linghong Cao, Rui Zeng, Zhi Zeng, Zhi Wan and 1 more

Erratum issuedOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 106 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Dongze LiDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China.
Lei YeDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China.
Yarong HeDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China.
Xiaoping CaoDepartment of Emergency Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Jining LiuDepartment of Emergency Medicine, Mianyang Central Hospital, Mianyang, China.
Wu ZhongDepartment of Emergency Medicine, Affiliated Hospital of Luzhou Medical College, Luzhou, China.
Linghong CaoDepartment of Emergency Medicine, Zigong No. 4 People's Hospital, Zigong, China.
Rui ZengDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Zhi ZengDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China.
Zhi WanDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China yuyuer@126.com 303680215@qq.com.
Yu CaoDepartment of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, China yuyuer@126.com 303680215@qq.com.
Sichuan University · CNAffiliated Hospital of North Sichuan Medical College · CNMianyang Central Hospital · CNSouthwest Medical University · CNZigong First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term association between the status of the false lumen and poor patient outcomes in acute aortic dissection (AAD) remains unclear. This systematic review and meta-analysis investigated whether the status of the false lumen was a predictor of poor long-term survival in AAD. METHODS AND

resultsEleven cohort studies (2924 participants) exploring the association between the false lumen status and long-term outcomes (>1 year) in AAD were included. All studies reported multivariate-adjusted hazard ratios (HRs) with 95% CIs for long-term outcomes, according to false lumen status. Pooled HRs for mortality and aortic events were computed and weighted using generic inverse-variance and random-effect modeling. Residual patent false lumen was an independent predictor of long-term mortality in AAD type A (HR, 1.71; 95% CI, 1.16-2.52; P=0.007) and type B (HR, 2.79; 95% CI, 1.80-4.32; P<0.001). AAD patients with residual patent false lumen exhibited an increased risk of aortic events (HR, 5.43; 95% CI, 2.95-9.99; P<0.001). Partial false lumen thrombosis was independently associated with long-term mortality in type B AAD (HR, 2.24; 95% CI, 1.37-3.65; P=0.001). This association was not observed in AAD type A patients (HR, 1.75; 95% CI, 0.88-3.45; P=0.211).

conclusionsThe false lumen status influences late outcomes in AAD. Residual patent false lumen is independently associated with poor long-term survival in AAD. However, only type B AAD patients with partial false lumen thrombosis had an increased late mortality risk.

Indexed as

Aortic AneurysmAortic DissectionHumansMortalityMultivariate AnalysisProportional Hazards ModelsThrombosisaortic dissectionfalse lumenmeta‐analysisthrombosis

Identifiers

PMID27166218
PMCPMC4889188
OpenAlexW2373790595

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.